Escherichia coli O157:H7

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 is a Gram-negative, rod-shaped bacterium that typically appears in pairs or as single cells. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. E. coli O157:H7 has an optimal temperature of approximately 37.0°C, which coincides with the average human body temperature, suggesting a significant association with warm-blooded hosts. The habitat of E. coli O157:H7 is primarily host-associated, indicating a strong relationship with the gastrointestinal tracts of animals, particularly ruminants such as cattle. This association highlights the bacterium's potential for transmission through the food chain, particularly in undercooked or contaminated food products. Furthermore, the facultative anaerobic nature of E. coli O157:H7 may confer advantages in fluctuating oxygen conditions within the gut environment, allowing it to maintain metabolic versatility. Unique to E. coli O157:H7 is its adaptation to thrive in host-associated niches, which not only facilitates its survival but may also influence its interactions with the host microbiome. This interplay could have implications for both microbial community dynamics and host health, underscoring the importance of understanding this pathogen's role in the broader ecological context of gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Escherichia coli O157:H7

Accession NumberNZ_CP017669.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4581 genes

Non-Coding Genes

1004 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
incfii family plasmid replication initiator repaCAM50_RS27370Not Available+1 - 85832717.6
copg family ribbon-helix-helix proteinCAM50_RS27385Not Available+1771 - 205510475.5
type ii toxin-antitoxin system rele/pare family toxinCAM50_RS27390Not Available+2055 - 233010736.0
hypothetical proteinCAM50_RS27395Not Available+2425 - 26318001.41
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27400Not Available-2731 - 29468215.67
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27405Not Available-2990 - 355621523.5
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27410Not Available-3556 - 397216036.6
hypothetical proteinCAM50_RS27415Not Available-3972 - 41576876.23
catalase/peroxidase katpCAM50_RS27420Not Available+4334 - 654481798.5
cytochrome b562CAM50_RS27425Not Available+6588 - 697714582.7

Displaying genes 1 – 10 of 11382 in total

Pathways

12367 pathways

Metabolites

790 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001462ubiquinone-0C9H10O4Chemical structure of ubiquinone-0605-94-7
Average182.1733Da
Monoisotopic182.057908808Da
BASm0001463alpha-L-rhamnoseC6H12O5Chemical structure of alpha-L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.068473494Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001785(2R,3R)-tartrateC4H6O6Chemical structure of (2R,3R)-tartrate87-69-4
Average150.0868Da
Monoisotopic150.0164379Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001885Tetra-mu3-sulfido-tetrairon(1+)Fe4S4Chemical structure of Tetra-mu3-sulfido-tetrairon(1+)Not available
Average351.62Da
Monoisotopic351.62748Da
BASm00021245-dehydro-4-deoxy-D-glucarateC6H6O7Chemical structure of 5-dehydro-4-deoxy-D-glucarateNot available
Average190.1076Da
Monoisotopic190.0113525Da
BASm00021923-(2,3-dihydroxyphenyl)propanoateC9H9O4Chemical structure of 3-(2,3-dihydroxyphenyl)propanoateNot available
Average181.1654Da
Monoisotopic181.0500838Da
BASm0002198beta-D-ribofuranoseC5H10O5Chemical structure of beta-D-ribofuranose50-69-1
Average150.1299Da
Monoisotopic150.05282343Da

Displaying 11–20 of 790 metabolites