Escherichia coli str. HPCN26

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain HPCN26 is a Gram-negative, rod-shaped bacterium typically found in pairs or as single cells. It is classified as a facultative anaerobe, indicating its ability to grow in both aerobic and anaerobic environments. This strain thrives optimally at a temperature of 37.0°C, which corresponds to the average body temperature of warm-blooded hosts, suggesting its adaptation to a host-associated habitat. As a member of the Escherichia coli species, HPCN26 likely shares common physiological traits with other strains, including versatility in nutrient utilization and metabolic pathways. The facultative anaerobic nature allows it to survive in various environments, including those within the gastrointestinal tract of hosts, where oxygen levels may fluctuate. This adaptability is crucial for colonization, survival, and potential interactions with the host's immune system. The ecological significance of Escherichia coli HPCN26 may extend beyond its basic metabolic capabilities, as it may play a role in the microbial communities associated with its host, contributing to the balance of gut microbiota. The presence of such strains highlights the importance of understanding microbial dynamics within host-associated environments, which can influence nutrient absorption and overall health. Further research on HPCN26 could provide insights into its specific roles within these complex ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainHPCN26

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. HPCN26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

UNVERIFIED_CONTAM: Escherichia coli strain HPCN26 Scaffold_1614,

Gene Summary

Adenine Count

1359008 bp

Thymine Count

1364318 bp

Guanine Count

1328836 bp

Cytosine Count

1338252 bp

Genome Length

5390414 bp

Protein-coding Genes

5232 genes

Non-Coding Genes

291 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permeaseDQE83_18555Not AvailablePositive3762463 - 376346134517.7
alcohol dehydrogenaseDQE83_18560Not AvailablePositive3763527 - 376458838097.1
aldose 1-epimeraseDQE83_18565Not AvailablePositive3764600 - 376547232643.2
doxx family proteinDQE83_18570Not AvailableNegative3765519 - 376594115198.3
phenylpropionate dioxygenase ferredoxin reductase subunitDQE83_18575Not AvailableNegative3766038 - 376724043791.4
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenaseDQE83_18580Not AvailableNegative3767250 - 376806228470.3
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunitDQE83_18585Not AvailableNegative3768059 - 376837911329.3
3-phenylpropionate/cinnamic acid dioxygenase subunit betaDQE83_18590Not AvailableNegative3768379 - 376889720536.3
3-phenylpropionate/cinnamic acid dioxygenase subunit alphaDQE83_18595Not AvailableNegative3768894 - 377025551111.8
dna-binding transcriptional regulator hcarDQE83_18600Not AvailablePositive3770391 - 377128132847.2

Displaying genes 3751 – 3760 of 5523 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total