Bordetella pertussis

Gram-negativeRodAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Alcaligenaceae

Genus

Bordetella

Description

Bordetella pertussis is a Gram-negative, rod-shaped bacterium that is classified as an aerobic mesophile, with an optimal growth temperature of 35.0 °C. This microbe is characterized by possessing two cellular membranes and true flagella, which may play a role in its motility within host-associated habitats. Bordetella pertussis is known to have two replicons, indicating a complex genomic structure that supports its interaction with host systems. The bacterium's ecological niche is primarily within hosts, suggesting that its lifestyle is closely tied to the biological dynamics of its environment. The genome of Bordetella pertussis has been sequenced, with accessions available under NZ_CP025530.1 and UFTT00000000.1, providing valuable information for further studies on its genetics and pathogenic mechanisms. Understanding the traits of Bordetella pertussis not only sheds light on its biological characteristics but also underscores the importance of host-associated microbes in maintaining ecological balance and influencing human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyAlcaligenaceae
GenusBordetella
SpeciesBordetella pertussis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNA
Flagellar presenceYes
Number of membranes2
Image of Bordetella pertussis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipNot Available
Host(s)Homo sapiens, Primates, Mammalia
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bordetella pertussis strain D236 chromosome, complete genome.

Gene Summary

Adenine Count

689229 bp

Thymine Count

694662 bp

Guanine Count

1452996 bp

Cytosine Count

1448441 bp

Genome Length

4285328 bp

Protein-coding Genes

3999 genes

Non-Coding Genes

98 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dtdp-glucose 4,6-dehydrataseCYO81_RS00580Not AvailableNegative107380 - 10844138964.0
is481-like element is481 family transposaseCYO81_RS00585Not AvailableNegative108477 - 10942735685.9
indolepyruvate ferredoxin oxidoreductase family proteinCYO81_RS00590Not AvailableNegative109526 - 11015321982.0
cystathionine beta-lyaseCYO81_RS00595Not AvailablePositive110327 - 11152043325.9
thiol:disulfide interchange protein dsba/dsblCYO81_RS00600Not AvailableNegative111602 - 11223122785.3
spor domain-containing proteinCYO81_RS00605Not AvailableNegative112293 - 11297623543.4
arginine--trna ligaseCYO81_RS00610Not AvailableNegative112986 - 11466861390.9
duf1840 domain-containing proteinCYO81_RS00615Not AvailablePositive114956 - 11530312539.9
hypothetical proteinCYO81_RS00620Not AvailablePositive115394 - 11571111257.5
is110-like element is1663 family transposaseCYO81_RS00625Not AvailablePositive115994 - 11701036629.5

Displaying genes 161 – 170 of 8077 in total

Pathways

22 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

185 records
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Mass search
Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da

Displaying 1–10 of 185 metabolites

Health Effects

Health ConditionRelationReference
Whooping coughCausesPMC12065220
Whooping coughCausesPMC2653234
Respiratory diseasesCausesPMC4618060
PneumoniaCausesPMC4618060
Whooping coughCausesPMC4618060
Whooping coughCausesPMC1965479
PertussisCausesPMC1965479
PertussisCausesPMC7498569
Whooping coughCausesPMC7498569
Whooping coughCausesPMC8076611

Displaying health effects 1 – 10 of 14 in total