Neisseria gonorrhoeae

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae is a type of bacteria that thrives in temperatures between 32°C and 40°C, making it a mesophilic organism. It is a heterotroph, utilizing a combination of carbohydrates and amino acids as its primary energy source. This microbe produces energy through a process called respiration, which involves the breakdown of glucose and other organic compounds in the presence of oxygen. When stained with a Gram stain, N. gonorrhoeae appears as a Gram-negative bacterium, characterized by an outer membrane containing lipopolysaccharides and lipids. In terms of shape, this bacterium is a diplococcus, meaning it forms pairs of spherical cells. N. gonorrhoeae can be found in various body sites, including the genital and urinary tracts of humans, as well as the throat and eyes. It is an obligate aerobe, requiring the presence of oxygen to survive. This microbe is able to tolerate a wide range of oxygen concentrations, making it a versatile inhabitant of the human body. One of the most significant aspects of N. gonorrhoeae is its ability to cause serious infections, particularly in the genital and urinary tracts. Gonorrhea, the sexually transmitted disease caused by this bacterium, can lead to severe consequences if left untreated, including infertility, pelvic inflammatory disease, and disseminated infection. The World Health Organization (WHO) estimates that there are over 80 million cases of gonorrhea worldwide each year, highlighting the significant public health burden of this microbe. Furthermore, N. gonorrhoeae has developed resistance to many antibiotics, making the treatment of gonorrhea increasingly challenging. This bacterium's ability to adapt to changing environments and develop resistance to antimicrobial agents further underscores the importance of continued research and public health efforts to combat this significant public health threat. Overall, Neisseria gonorrhoeae is a significant microbe that requires careful management and attention to prevent the spread of disease and mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae

Accession NumberSURC00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

2631 genes

Non-Coding Genes

106 genes

# of Chromosomes/Plasmids

24

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Hypothetical proteinEPH42_08100Not Available+1397185 - 13974188719.84
hypothetical proteinEPH42_08105Not Available+1397462 - 139786915587.5
Hypothetical proteinEPH42_08110Not Available+1397960 - 139829512395.7
Putative antirepressor protein antEPH42_08115Not Available+1398663 - 139953231537.8
AttlNot AvailableNot Available+1399547 - 1399562Not Available
Terminase small subunitEPH42_08120Not Available+1399825 - 140027416845.0
Hypothetical proteinEPH42_08125Not Available+1400336 - 140175752437.1
Portal and muf-like fusion proteinEPH42_08130Not Available+1401754 - 140390178940.6
Prohead proteaseEPH42_08135Not Available+1403969 - 140512640328.2
Major capsid proteinEPH42_08140Not Available+1405167 - 140666652594.3

Displaying genes 1 – 10 of 56816 in total

Pathways

23 pathways

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0012554N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanineC37H57N7O20Not availableNot available
Average919.893Da
Monoisotopic919.366934423Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da
BASm0014182Vaccenic acidC18H34O2Chemical structure of Vaccenic acidNULL
Average282.468Da
Monoisotopic282.255880335Da
BASm0014219Palmitoleic acidC16H30O2Chemical structure of Palmitoleic acidNULL
Average254.4082Da
Monoisotopic254.224580204Da
BASm0014222DiethanolamineC4H11NO2Chemical structure of DiethanolamineNULL
Average105.1356Da
Monoisotopic105.078978601Da

Displaying 1–10 of 88 metabolites