Moraxella catarrhalis

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Moraxella

Description

Moraxella catarrhalis is a Gram-negative, non-motile coccus that thrives in host-associated environments, exhibiting aerobic metabolic activity. This bacterium is classified as mesophilic, indicating an optimal growth temperature typically found in warm-blooded hosts. Morphologically, Moraxella catarrhalis possesses two cellular membranes, consistent with its Gram-negative classification. The organism is characterized by the presence of five replicons in its genome, which suggests a complex genetic architecture that may contribute to its adaptability in various environments. The genome of Moraxella catarrhalis is represented by multiple accessions, including LXHT00000000.1 and LXHQ00000000.1, among others, indicating a rich repository of genetic information for further study. As a free-living organism within host-associated habitats, Moraxella catarrhalis may play a role in the microbial communities of its hosts, which could influence both the host's health and the dynamics of microbial interactions. Its unique ecological niche and the genetic diversity reflected in its genome may provide insights into its interactions with other microorganisms and its potential roles in host-associated microbiomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusMoraxella
SpeciesMoraxella catarrhalis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Moraxella catarrhalis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Macaca mulatta, Chinchilla
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Moraxella catarrhalis strain C031 B620ctg48, whole genome shotgun

Gene Summary

Adenine Count

572216 bp

Thymine Count

571002 bp

Guanine Count

397975 bp

Cytosine Count

413446 bp

Genome Length

1954639 bp

Protein-coding Genes

1961 genes

Non-Coding Genes

72 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lsu ribosomal protein l23p l23aeAO365_1414A5WCJ2Negative1370548 - 137087711865.3
lsu ribosomal protein l4p l1eAO365_1415A5WCJ1Negative1370874 - 137147621916.6
lsu ribosomal protein l3p l3eAO365_1416A5WCJ0Negative1371491 - 137212922309.8
ssu ribosomal protein s10p s20eAO365_1417Q4FUF7Negative1372182 - 137249311631.1
cytoplasmic axial filament protein cafa and ribonuclease gAO365_1418A0A0H3NGK0Negative1372895 - 137452361521.2
septum formation protein mafAO365_1419Q1QDI9Negative1374712 - 137532322088.8
hypothetical proteinAO365_1420Not AvailablePositive1375440 - 13755775443.84
hypothetical proteinAO365_1421P58528Positive1375640 - 137592710329.3
hypothetical proteinAO365_1422Q49091Positive1376021 - 137749952862.5
beta-lactamaseAO365_1423Q59514Positive1377575 - 137851635384.7

Displaying genes 1421 – 1430 of 9220 in total

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000315acetylpyruvateC5H6O4Chemical structure of acetylpyruvateNot available
Average130.099Da
Monoisotopic130.0266087Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da

Displaying 1–10 of 135 metabolites

Health Effects

Health ConditionRelationReference
SinusitisCausesPMC12375837
Otitis mediaCausesPMC3695778
Respiratory infectionsCausesPMC3695778
Copd exacerbationCausesPMC7362441
Otitis mediaCausesPMC7362441
Respiratory tract infectionCausesPMC4765729
Childhood otitis mediaCausesPMC4765729
Respiratory tract infectionsCausesPMC4765729
Middle ear infectionsCausesPMC9318310
Copd-related infectionsCausesPMC3417516

Displaying health effects 1 – 10 of 22 in total