Burkholderia cepacia

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia cepacia is a gram-negative, rod-shaped bacterium that thrives in a wide range of environments. It belongs to the category of chemoheterotrophs, meaning it derives its energy from the breakdown of organic compounds and uses carbon dioxide as its energy source. This microbe is capable of aerobic respiration, which involves the use of oxygen to generate energy. In terms of its gram stain, Burkholderia cepacia has a negatively-staining cell wall, indicating the presence of a lipopolysaccharide layer. Physiologically, B. cepacia exhibits a bipolar staining pattern, where it has a Gram-negative cell wall with a distinctive "safe" zone at the ends, giving it a polar appearance. This unique morphology is a characteristic of its species. Furthermore, it can be found in various environments, including soil, water, and plants, making it a ubiquitous microorganism. In terms of its oxygen preference, B. cepacia is a facultative anaerobe, meaning it can grow and thrive in the presence or absence of oxygen. This adaptability allows it to colonize a wide range of environments, from aerobic to anaerobic niches. Additionally, it exhibits a preference for a moderately alkaline pH, typically found in environments with high levels of nutrients. Burkholderia cepacia has been recognized for its ability to form biofilms, complex communities of microorganisms attached to surfaces. This unique ability allows it to colonize diverse hosts, including humans, animals, and plants. In fact, its ability to infect individuals with compromised immune systems, such as those with cystic fibrosis, has garnered significant attention from researchers and clinicians. Despite its role as an opportunistic pathogen, B. cepacia has also been investigated for its potential applications in biotechnology and medicine. Its capacity to degrade pollutants, such as pesticides and heavy metals, has made it a valuable tool for environmental remediation. Furthermore, its antimicrobial properties have been explored for the development of novel antibiotics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia cepacia
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Burkholderia cepacia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia cepacia

Accession NumberLPKB00000000.1

Gene Summary

Adenine Count

1499531 bp

Thymine Count

1499971 bp

Guanine Count

2964604 bp

Cytosine Count

2970708 bp

Genome Length

8934814 bp

Protein-coding Genes

7719 genes

Non-Coding Genes

133 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Putative virion morphogenesis proteinWL94_20200Q01259-5044552 - 504586248877.9
Putative portal proteinWL94_20205P44225-5045852 - 504747159932.8
Hypothetical proteinWL94_20210Not Available-5047480 - 504925265938.9
hypothetical proteinWL94_20215Not Available-5049254 - 50494607504.0
Hypothetical proteinWL94_20220Not Available-5049470 - 504997017994.5
hypothetical proteinWL94_20225Not Available-5049976 - 50501826868.44
hypothetical proteinWL94_20230Not Available-5050179 - 505045410394.5
Hypothetical proteinWL94_20235Not Available-5050451 - 50506848766.14
Hypothetical proteinWL94_20240Not Available-5050694 - 505129620994.5
Hypothetical proteinWL94_20245Not Available-5051280 - 50515228680.65

Displaying genes 21 – 30 of 23432 in total

Pathways

23 pathways

Metabolites

555 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000234(3R)-hydroxybutanoate dimerC8H13O5Chemical structure of (3R)-hydroxybutanoate dimerNot available
Average189.188Da
Monoisotopic189.0768471Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm00002583-(carbamoylamino)propanoateC4H7N2O3Chemical structure of 3-(carbamoylamino)propanoateNot available
Average131.112Da
Monoisotopic131.046215673Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002634-(hydroxymethyl)benzenesulfonateC7H7O4SChemical structure of 4-(hydroxymethyl)benzenesulfonateNot available
Average187.19Da
Monoisotopic187.007053459Da
BASm00002654-formylbenzenesulfonateC7H5O4SChemical structure of 4-formylbenzenesulfonateNot available
Average185.17Da
Monoisotopic184.991403395Da

Displaying 1–10 of 555 metabolites