Burkholderia cepacia

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia cepacia is a gram-negative, rod-shaped bacterium that thrives in a wide range of environments. It belongs to the category of chemoheterotrophs, meaning it derives its energy from the breakdown of organic compounds and uses carbon dioxide as its energy source. This microbe is capable of aerobic respiration, which involves the use of oxygen to generate energy. In terms of its gram stain, Burkholderia cepacia has a negatively-staining cell wall, indicating the presence of a lipopolysaccharide layer. Physiologically, B. cepacia exhibits a bipolar staining pattern, where it has a Gram-negative cell wall with a distinctive "safe" zone at the ends, giving it a polar appearance. This unique morphology is a characteristic of its species. Furthermore, it can be found in various environments, including soil, water, and plants, making it a ubiquitous microorganism. In terms of its oxygen preference, B. cepacia is a facultative anaerobe, meaning it can grow and thrive in the presence or absence of oxygen. This adaptability allows it to colonize a wide range of environments, from aerobic to anaerobic niches. Additionally, it exhibits a preference for a moderately alkaline pH, typically found in environments with high levels of nutrients. Burkholderia cepacia has been recognized for its ability to form biofilms, complex communities of microorganisms attached to surfaces. This unique ability allows it to colonize diverse hosts, including humans, animals, and plants. In fact, its ability to infect individuals with compromised immune systems, such as those with cystic fibrosis, has garnered significant attention from researchers and clinicians. Despite its role as an opportunistic pathogen, B. cepacia has also been investigated for its potential applications in biotechnology and medicine. Its capacity to degrade pollutants, such as pesticides and heavy metals, has made it a valuable tool for environmental remediation. Furthermore, its antimicrobial properties have been explored for the development of novel antibiotics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia cepacia
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Burkholderia cepacia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia cepacia

Accession NumberLPKB00000000.1

Gene Summary

Adenine Count

1499531 bp

Thymine Count

1499971 bp

Guanine Count

2964604 bp

Cytosine Count

2970708 bp

Genome Length

8934814 bp

Protein-coding Genes

7719 genes

Non-Coding Genes

133 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Dam modification methylaseWL94_20100Not Available-5026388 - 502718830207.2
hypothetical proteinWL94_20105Not Available-5027329 - 502946475261.1
Tail proteinWL94_20110Not Available-5029538 - 503012521111.0
Baseplate j proteinWL94_20115P44240-5030122 - 503118937225.1
Hypothetical proteinWL94_20120Not Available-5031189 - 503153912945.4
Baseplate assembly proteinWL94_20125Not Available-5031605 - 503227023368.9
Mu-like prophage tail protein gppWL94_20130Not Available-5032267 - 503339740745.3
Tail/dna circulation proteinWL94_20135Not Available-5033381 - 503469447001.7
Bacteriophage tail length determination proteinWL94_20140Not Available-5034696 - 503695178317.5
hypothetical proteinWL94_20145Not Available-5037094 - 503748614004.2

Displaying genes 1 – 10 of 23432 in total

Pathways

23 pathways

Metabolites

555 records
Metabolite IDMetabolite nameStructureCAS number
BASm00008135-dehydro-D-fructoseC6H10O6Chemical structure of 5-dehydro-D-fructoseNot available
Average178.14Da
Monoisotopic178.047738042Da
BASm0000841L-arabinono-1,4-lactoneC5H8O5Chemical structure of L-arabinono-1,4-lactoneNot available
Average148.114Da
Monoisotopic148.037173358Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000899N-isopropylammelideC6H10N4O2Chemical structure of N-isopropylammelideNot available
Average170.172Da
Monoisotopic170.0803756Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0000934(R)-mandelamideC8H9NO2Chemical structure of (R)-mandelamideNot available
Average151.165Da
Monoisotopic151.0633285Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da
BASm0001065(S)-mandelateC8H7O3Chemical structure of (S)-mandelateNot available
Average151.142Da
Monoisotopic151.0400677Da

Displaying 41–50 of 555 metabolites