Burkholderia cepacia

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia cepacia is a gram-negative, rod-shaped bacterium that thrives in a wide range of environments. It belongs to the category of chemoheterotrophs, meaning it derives its energy from the breakdown of organic compounds and uses carbon dioxide as its energy source. This microbe is capable of aerobic respiration, which involves the use of oxygen to generate energy. In terms of its gram stain, Burkholderia cepacia has a negatively-staining cell wall, indicating the presence of a lipopolysaccharide layer. Physiologically, B. cepacia exhibits a bipolar staining pattern, where it has a Gram-negative cell wall with a distinctive "safe" zone at the ends, giving it a polar appearance. This unique morphology is a characteristic of its species. Furthermore, it can be found in various environments, including soil, water, and plants, making it a ubiquitous microorganism. In terms of its oxygen preference, B. cepacia is a facultative anaerobe, meaning it can grow and thrive in the presence or absence of oxygen. This adaptability allows it to colonize a wide range of environments, from aerobic to anaerobic niches. Additionally, it exhibits a preference for a moderately alkaline pH, typically found in environments with high levels of nutrients. Burkholderia cepacia has been recognized for its ability to form biofilms, complex communities of microorganisms attached to surfaces. This unique ability allows it to colonize diverse hosts, including humans, animals, and plants. In fact, its ability to infect individuals with compromised immune systems, such as those with cystic fibrosis, has garnered significant attention from researchers and clinicians. Despite its role as an opportunistic pathogen, B. cepacia has also been investigated for its potential applications in biotechnology and medicine. Its capacity to degrade pollutants, such as pesticides and heavy metals, has made it a valuable tool for environmental remediation. Furthermore, its antimicrobial properties have been explored for the development of novel antibiotics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia cepacia
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Burkholderia cepacia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia cepacia

Accession NumberLPKB00000000.1

Gene Summary

Adenine Count

1499531 bp

Thymine Count

1499971 bp

Guanine Count

2964604 bp

Cytosine Count

2970708 bp

Genome Length

8934814 bp

Protein-coding Genes

7719 genes

Non-Coding Genes

133 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Dam modification methylaseWL94_20100Not Available-5026388 - 502718830207.2
hypothetical proteinWL94_20105Not Available-5027329 - 502946475261.1
Tail proteinWL94_20110Not Available-5029538 - 503012521111.0
Baseplate j proteinWL94_20115P44240-5030122 - 503118937225.1
Hypothetical proteinWL94_20120Not Available-5031189 - 503153912945.4
Baseplate assembly proteinWL94_20125Not Available-5031605 - 503227023368.9
Mu-like prophage tail protein gppWL94_20130Not Available-5032267 - 503339740745.3
Tail/dna circulation proteinWL94_20135Not Available-5033381 - 503469447001.7
Bacteriophage tail length determination proteinWL94_20140Not Available-5034696 - 503695178317.5
hypothetical proteinWL94_20145Not Available-5037094 - 503748614004.2

Displaying genes 1 – 10 of 23432 in total

Pathways

23 pathways

Metabolites

555 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000288aminohydroquinoneC6H7NO2Chemical structure of aminohydroquinoneNot available
Average125.127Da
Monoisotopic125.0476785Da
BASm0000305tetrathionateO6S4Chemical structure of tetrathionateNot available
Average224.24Da
Monoisotopic223.8588696Da
BASm0000315acetylpyruvateC5H6O4Chemical structure of acetylpyruvateNot available
Average130.099Da
Monoisotopic130.0266087Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da

Displaying 11–20 of 555 metabolites