Helicobacter pylori str. ZH97

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH97 is a Gram-negative, spiral-shaped bacterium that typically exists as single cells and is adapted to a microaerophilic environment. This strain thrives optimally at a temperature of 37.0°C, aligning with the physiological conditions found in the human stomach, its primary habitat. Helicobacter pylori is known for its association with host organisms, where it colonizes the gastric mucosa and may influence various gastrointestinal processes. The microaerophilic nature of H. pylori indicates its requirement for reduced levels of oxygen for growth, distinguishing it from strictly aerobic and anaerobic organisms. This trait is crucial for its survival in the harsh acidic environment of the stomach, where it can utilize the available oxygen while avoiding the detrimental effects of higher concentrations. Overall, Helicobacter pylori strain ZH97 exemplifies the intricate adaptations that bacteria can develop to thrive in specific host-associated niches, particularly in environments characterized by fluctuating oxygen levels and extreme acidity. Understanding these traits provides insight into the ecological roles of H. pylori within the human gastrointestinal tract and may inform further research into its interactions with host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH97

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH97
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH97 51, whole genome shotgun sequence.

Gene Summary

Adenine Count

507028 bp

Thymine Count

502583 bp

Guanine Count

320434 bp

Cytosine Count

319968 bp

Genome Length

1653855 bp

Protein-coding Genes

1500 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aldehyde dehydrogenase family proteinEC547_01825Not AvailableNegative367227 - 370784134983.0
hypothetical proteinEC547_01830Not AvailablePositive371112 - 3713217636.08
hypothetical proteinEC547_01840Not AvailablePositive372405 - 37307325779.5
hypothetical proteinEC547_01845Not AvailablePositive373108 - 37553492493.5
hypothetical proteinEC547_01850Not AvailablePositive375531 - 37610021686.0
type vii secretion proteinEC547_01855Not AvailablePositive376116 - 37637610444.1
smi1/knr4 family proteinEC547_01865Not AvailablePositive377721 - 37814616288.5
hypothetical proteinEC547_01870Not AvailablePositive378148 - 37849813862.3
urease accessory protein uredEC547_01880Not AvailableNegative380956 - 38175329710.9
urease accessory protein uregEC547_01885Not AvailableNegative381753 - 38235221956.6

Displaying genes 351 – 360 of 1542 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total