Helicobacter pylori str. ZH93

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH93 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns well with its habitat as it is closely associated with the host, typically residing within the gastric mucosa of humans and other mammals. The microaerophilic nature of H. pylori ZH93 indicates a requirement for low levels of oxygen, which is consistent with the oxygen-limited conditions of the stomach environment. This adaptation allows the microbe to maintain its viability and metabolic functions in a habitat where higher oxygen levels would be detrimental. Given its host-associated habitat, H. pylori ZH93 likely plays a significant role in the complex interactions within the gastric microbiome, including potential influences on host immune responses and nutrient absorption. Further studies could elucidate the specific ecological niches it occupies and its interactions with both the host and other microbial communities in the gastrointestinal tract. Understanding these dynamics may provide insights into the broader implications of H. pylori in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH93

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH93
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH93 57, whole genome shotgun sequence.

Gene Summary

Adenine Count

481289 bp

Thymine Count

490827 bp

Guanine Count

303997 bp

Cytosine Count

311902 bp

Genome Length

1592263 bp

Protein-coding Genes

1439 genes

Non-Coding Genes

37 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
1-deoxy-d-xylulose-5-phosphate reductoisomeraseEC543_01855Not AvailableNegative361433 - 36253940398.7
phosphatidate cytidylyltransferaseEC543_01860Not AvailableNegative362540 - 36334028843.1
slc13 family permeaseEC543_01865Not AvailableNegative363353 - 36499959381.6
trna uridine-5-carboxymethylaminomethyl(34) synthesis enzyme mnmgEC543_01870Not AvailablePositive365096 - 36696169702.1
succinyl-diaminopimelate desuccinylaseEC543_01875Not AvailablePositive366972 - 36813842936.9
sel1-like repeat protein hcpaEC543_01880Not AvailablePositive368219 - 36897127451.1
molecular chaperone htpgEC543_01885Not AvailableNegative369172 - 37103771160.9
outer membrane beta-barrel protein hofaEC543_01890Not AvailableNegative371141 - 37249352616.6
glycosyltransferase family 8 proteinEC543_01895Not AvailablePositive372686 - 37382845057.7
mrp family atp-binding proteinEC543_01900Not AvailableNegative373888 - 37512044952.0

Displaying genes 351 – 360 of 1476 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total