Helicobacter pylori str. ZH93

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH93 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns well with its habitat as it is closely associated with the host, typically residing within the gastric mucosa of humans and other mammals. The microaerophilic nature of H. pylori ZH93 indicates a requirement for low levels of oxygen, which is consistent with the oxygen-limited conditions of the stomach environment. This adaptation allows the microbe to maintain its viability and metabolic functions in a habitat where higher oxygen levels would be detrimental. Given its host-associated habitat, H. pylori ZH93 likely plays a significant role in the complex interactions within the gastric microbiome, including potential influences on host immune responses and nutrient absorption. Further studies could elucidate the specific ecological niches it occupies and its interactions with both the host and other microbial communities in the gastrointestinal tract. Understanding these dynamics may provide insights into the broader implications of H. pylori in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH93

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH93
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH93 57, whole genome shotgun sequence.

Gene Summary

Adenine Count

481289 bp

Thymine Count

490827 bp

Guanine Count

303997 bp

Cytosine Count

311902 bp

Genome Length

1592263 bp

Protein-coding Genes

1439 genes

Non-Coding Genes

37 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
spor domain-containing proteinEC543_05560Not AvailableNegative1088055 - 108880128794.3
duf904 domain-containing proteinEC543_05565Not AvailablePositive1089002 - 10892328621.3
hypothetical proteinEC543_05570Not AvailablePositive1089245 - 10894819297.04
primosomal protein n'EC543_05575Not AvailablePositive1089466 - 109132570448.3
carboxy-s-adenosyl-l-methionine synthase cmoaEC543_05580Not AvailableNegative1091413 - 109213228087.3
superoxide dismutaseEC543_05585Not AvailableNegative1092184 - 109282524502.8
thiol peroxidaseEC543_05590Not AvailablePositive1093049 - 109354918323.4
chemotaxis protein chewEC543_05595Not AvailableNegative1093810 - 109430718922.8
hybrid sensor histidine kinase/response regulatorEC543_05600Not AvailableNegative1094304 - 109671589587.6
chemotaxis signal transduction protein chevEC543_05605Not AvailableNegative1096772 - 109770735652.0

Displaying genes 1051 – 1060 of 1476 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total