Helicobacter pylori str. ZH75

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH75 is a Gram-negative, microaerophilic bacterium characterized by its distinctive spirilla shape and solitary cell arrangement. This strain thrives optimally at a temperature of 37.0°C, suggesting a close association with warm-blooded hosts, where it typically resides in the gastric environment. As a member of the Helicobacter genus, H. pylori str. ZH75’s microaerophilic nature indicates its requirement for reduced oxygen levels, which aligns with its adaptation to the acidic conditions of the stomach. The bacterium's habitat is exclusively host-associated, emphasizing its specialized role in the gastric microbiome of various organisms. The unique morphological and physiological traits of H. pylori str. ZH75 may offer insights into its ecological niche, particularly its potential interactions within the host's gastric environment. Understanding these interactions could provide valuable information about the organism's role in host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH75

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH75
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH75 57, whole genome shotgun sequence.

Gene Summary

Adenine Count

494773 bp

Thymine Count

491286 bp

Guanine Count

314061 bp

Cytosine Count

315728 bp

Genome Length

1620096 bp

Protein-coding Genes

1466 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Methionine adenosyltransferaseEC524_06275Not AvailableNegative1268057 - 126921442434.7
Hypothetical proteinEC524_06280Not AvailablePositive1269513 - 126984812507.3
AttlNot AvailableNot AvailablePositive1269743 - 1269755Not Available
Integrase/recombinaseEC524_06285Not AvailablePositive1269973 - 127117442413.8
Hypothetical proteinEC524_06290Not AvailablePositive1271171 - 12713928886.82
Putative transcriptional regulatorEC524_06295Not AvailablePositive1271402 - 127171011989.8
Hypothetical proteinEC524_06300Not AvailablePositive1271707 - 12718083969.77
Antitoxin hicbEC524_06305Not AvailablePositive1271887 - 12721057999.64
Ycfa-like family protein, putative toxin componentEC524_06310Not AvailablePositive1272098 - 12722927494.4
Putative transposase, is607 familyEC524_06315Not AvailablePositive1272289 - 127292124211.5

Displaying genes 1 – 10 of 1530 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Peptic ulcer diseaseCausesPMC3433584
Gastric cancerCausesPMC3433584
Gastric adenocarcinomaCausesPMC3561388
Peptic ulcer diseaseCausesPMC3561388
Gastric mucosa-associated lymphoid tissue (malt) lymphomaCausesPMC3561388
GastritisCausesPMC3780442
Peptic ulcer diseaseCausesPMC3780442
Gastric mucosa-associated lymphoid tissue (malt) lymphomaCausesPMC3780442
GastritisCausesPMC4433339
UlcersCausesPMC4433339

Displaying health effects 81 – 90 of 94 in total