Helicobacter pylori str. ZH75

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH75 is a Gram-negative, microaerophilic bacterium characterized by its distinctive spirilla shape and solitary cell arrangement. This strain thrives optimally at a temperature of 37.0°C, suggesting a close association with warm-blooded hosts, where it typically resides in the gastric environment. As a member of the Helicobacter genus, H. pylori str. ZH75’s microaerophilic nature indicates its requirement for reduced oxygen levels, which aligns with its adaptation to the acidic conditions of the stomach. The bacterium's habitat is exclusively host-associated, emphasizing its specialized role in the gastric microbiome of various organisms. The unique morphological and physiological traits of H. pylori str. ZH75 may offer insights into its ecological niche, particularly its potential interactions within the host's gastric environment. Understanding these interactions could provide valuable information about the organism's role in host health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH75

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH75
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH75 57, whole genome shotgun sequence.

Gene Summary

Adenine Count

494773 bp

Thymine Count

491286 bp

Guanine Count

314061 bp

Cytosine Count

315728 bp

Genome Length

1620096 bp

Protein-coding Genes

1466 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
virb3 type iv secretion proteinEC524_00190Not AvailableNegative34029 - 3428910214.7
virb2 type iv secretion proteinEC524_00195Not AvailableNegative34290 - 3459210790.8
hypothetical proteinEC524_00205Not AvailableNegative36509 - 3727329927.5
cag pathogenicity island proteinEC524_00215Not AvailablePositive37480 - 376958413.46
fad-dependent thymidylate synthaseEC524_00220Not AvailableNegative37727 - 3835324025.8
glutamine--fructose-6-phosphate transaminase (isomerizing)EC524_00225Not AvailableNegative38375 - 4016867226.8
duf2443 domain-containing proteinEC524_00230Not AvailableNegative40169 - 404089099.29
purine-nucleoside phosphorylaseEC524_00235Not AvailableNegative40453 - 4099520046.4
chromosomal replication initiator protein dnaaEC524_00240Not AvailablePositive41148 - 4251551473.9
competence proteinEC524_00245Not AvailablePositive42743 - 4418254690.3

Displaying genes 61 – 70 of 1530 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total