Helicobacter pylori str. ZH72

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH72 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe demonstrates an optimal growth temperature of 37.0°C, indicating its adaptation to the human body, where it is primarily found as a host-associated organism. H. pylori str. ZH72 exhibits microaerophilic oxygen requirements, thriving in environments with reduced oxygen levels, which is characteristic of its niche in the gastric mucosa. The unique morphology of H. pylori, coupled with its specific growth conditions, underscores its specialized lifestyle in the gastric environment. The microaerophilic nature of this strain may suggest an evolutionary adaptation allowing it to evade the host's immune response while exploiting the nutrient-rich conditions of the stomach lining. Understanding the traits of H. pylori str. ZH72 can provide insights into its ecological role within the human gastric microbiome, as it may influence local pH levels and interact with other microbial communities present in the host's gastrointestinal tract. Further investigation into the ecological interactions and metabolic capabilities of this strain could enhance our understanding of its role in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH72

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH72
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH72 40, whole genome shotgun sequence.

Gene Summary

Adenine Count

492536 bp

Thymine Count

487957 bp

Guanine Count

312949 bp

Cytosine Count

312723 bp

Genome Length

1609121 bp

Protein-coding Genes

1451 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s ribosomal rnaNot AvailableNot AvailablePositive611 - 2119Not Available
hypothetical proteinEC520_00005Not AvailableNegative2 - 78129332.3
peptidylprolyl isomeraseEC520_00010Not AvailablePositive899 - 139017673.1
carbon storage regulatorEC520_00015Not AvailablePositive1409 - 16398440.41
4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol kinaseEC520_00020Not AvailablePositive1636 - 244230296.5
ssra-binding proteinEC520_00025Not AvailablePositive2439 - 289717797.1
tonb-system energizer exbbEC520_00030Not AvailablePositive2900 - 335216651.9
biopolymer transporter exbdEC520_00035Not AvailablePositive3363 - 376415042.4
50s ribosomal protein l34EC520_00040Not AvailablePositive3836 - 39705246.63
ribonuclease p protein componentEC520_00045Not AvailablePositive3930 - 441518738.0

Displaying genes 1 – 10 of 1492 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Peptic ulcersCausesPMC11811748
Malt lymphomaCausesPMC11811748
Gastric adenocarcinomaCausesPMC11811748
GastritisCausesPMC2213429
Peptic ulcer diseaseCausesPMC2844414
Gastric cancerCausesPMC2844414
Chronic active gastritisCausesPMC3382622
GastritisCausesPMC3433584
Peptic ulcersCausesPMC3433584
Gastric malignancyCausesPMC3433584

Displaying health effects 71 – 80 of 94 in total