Helicobacter pylori str. ZH47

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH47 is a Gram-negative bacterium characterized by its spirilla shape and typically found as single cells. This microbe demonstrates a microaerophilic oxygen requirement, indicating its preference for environments with reduced oxygen levels, which is consistent with its association with host habitats. Optimal growth occurs at a temperature of 37.0 °C, aligning with the physiological conditions found in the gastrointestinal tract of mammals, particularly humans. As a host-associated organism, H. pylori str. ZH47 is likely adapted to thrive in the acidic environment of the stomach, where it may play a role in the complex microbial community residing there. The unique morphology of this strain, along with its specific growth requirements, suggests potential adaptations that allow it to colonize and persist in such a challenging niche. Further investigation into its interactions within the host environment may provide insights into its ecological role and its impact on host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH47

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH47 41, whole genome shotgun sequence.

Gene Summary

Adenine Count

480406 bp

Thymine Count

482096 bp

Guanine Count

307106 bp

Cytosine Count

306888 bp

Genome Length

1579528 bp

Protein-coding Genes

1437 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
site-specific dna-methyltransferaseECC45_00005Not AvailableNegative1 - 42616956.5
16s ribosomal rnaNot AvailableNot AvailablePositive496 - 2004Not Available
dna cytosine methyltransferaseECC45_00010Not AvailableNegative423 - 186854840.6
sodium/proline symporter putpECC45_00015Not AvailableNegative1908 - 339854123.3
aldehyde dehydrogenase family proteinECC45_00020Not AvailableNegative3425 - 6982135140.0
hypothetical proteinECC45_00025Not AvailablePositive7304 - 75137636.01
m proteinECC45_00030Not AvailablePositive7822 - 854127432.3
hypothetical proteinECC45_00035Not AvailablePositive8543 - 931029553.9
hypothetical proteinECC45_00040Not AvailablePositive9326 - 1046844451.9
type vii secretion proteinECC45_00055Not AvailablePositive12328 - 1258810390.0

Displaying genes 1 – 10 of 1477 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Peptic ulcer diseaseCausesPMC5203880
Gastric adenocarcinomaCausesPMC5203880
Mucosa-associated lymphoid tissue (malt) lymphomaCausesPMC5203880
Peptic ulcer diseaseCausesPMC7037374
GastritisCausesPMC7037374
Gastric cancerCausesPMC7037374
Functional dyspepsiaCausesPMC7037374
GastritisCausesPMC7459201
Gastric cancerCausesPMC7459201
Intestinal diseasesCausesPMC7459201

Displaying health effects 31 – 40 of 94 in total