Helicobacter pylori str. ZH47

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH47 is a Gram-negative bacterium characterized by its spirilla shape and typically found as single cells. This microbe demonstrates a microaerophilic oxygen requirement, indicating its preference for environments with reduced oxygen levels, which is consistent with its association with host habitats. Optimal growth occurs at a temperature of 37.0 °C, aligning with the physiological conditions found in the gastrointestinal tract of mammals, particularly humans. As a host-associated organism, H. pylori str. ZH47 is likely adapted to thrive in the acidic environment of the stomach, where it may play a role in the complex microbial community residing there. The unique morphology of this strain, along with its specific growth requirements, suggests potential adaptations that allow it to colonize and persist in such a challenging niche. Further investigation into its interactions within the host environment may provide insights into its ecological role and its impact on host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH47

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH47 41, whole genome shotgun sequence.

Gene Summary

Adenine Count

480406 bp

Thymine Count

482096 bp

Guanine Count

307106 bp

Cytosine Count

306888 bp

Genome Length

1579528 bp

Protein-coding Genes

1437 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l17ECC45_04530Not AvailableNegative903894 - 90424413365.2
dna-directed rna polymerase subunit alphaECC45_04535Not AvailableNegative904244 - 90527838500.4
30s ribosomal protein s4ECC45_04540Not AvailableNegative905290 - 90591624003.1
30s ribosomal protein s11ECC45_04545Not AvailableNegative905926 - 90632114016.1
30s ribosomal protein s13ECC45_04550Not AvailableNegative906344 - 90670613602.7
50s ribosomal protein l36ECC45_04555Not AvailableNegative906710 - 9068234321.68
translation initiation factor if-1ECC45_04560Not AvailableNegative906902 - 9071208348.36
type i methionyl aminopeptidaseECC45_04565Not AvailableNegative907120 - 90788127552.6
protein translocase subunit secyECC45_04570Not AvailableNegative907881 - 90914345831.7
50s ribosomal protein l15ECC45_04575Not AvailableNegative909186 - 90958714661.9

Displaying genes 861 – 870 of 1477 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total