Helicobacter pylori str. ZH47

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH47 is a Gram-negative bacterium characterized by its spirilla shape and typically found as single cells. This microbe demonstrates a microaerophilic oxygen requirement, indicating its preference for environments with reduced oxygen levels, which is consistent with its association with host habitats. Optimal growth occurs at a temperature of 37.0 °C, aligning with the physiological conditions found in the gastrointestinal tract of mammals, particularly humans. As a host-associated organism, H. pylori str. ZH47 is likely adapted to thrive in the acidic environment of the stomach, where it may play a role in the complex microbial community residing there. The unique morphology of this strain, along with its specific growth requirements, suggests potential adaptations that allow it to colonize and persist in such a challenging niche. Further investigation into its interactions within the host environment may provide insights into its ecological role and its impact on host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH47

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH47 41, whole genome shotgun sequence.

Gene Summary

Adenine Count

480406 bp

Thymine Count

482096 bp

Guanine Count

307106 bp

Cytosine Count

306888 bp

Genome Length

1579528 bp

Protein-coding Genes

1437 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sel1-like repeat protein hcpaECC45_00815Not AvailableNegative159768 - 16052027352.1
succinyl-diaminopimelate desuccinylaseECC45_00820Not AvailableNegative160605 - 16177142844.9
trna uridine-5-carboxymethylaminomethyl(34) synthesis enzyme mnmgECC45_00825Not AvailableNegative161782 - 16364769692.1
slc13 family permeaseECC45_00830Not AvailablePositive163743 - 16540159563.9
phosphatidate cytidylyltransferaseECC45_00835Not AvailablePositive165414 - 16621428816.9
1-deoxy-d-xylulose-5-phosphate reductoisomeraseECC45_00840Not AvailablePositive166215 - 16732140385.6
ybhb/ybcl family raf kinase inhibitor-like proteinECC45_00850Not AvailableNegative168570 - 16912120676.9
helix-turn-helix domain-containing proteinECC45_00855Not AvailablePositive169267 - 16972817871.8
cysteine desulfurase iscsECC45_00860Not AvailablePositive169899 - 17106242448.0
iron-sulfur cluster assembly scaffold protein nifuECC45_00865Not AvailablePositive171084 - 17206436406.9

Displaying genes 151 – 160 of 1477 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total