Helicobacter pylori str. ZH47

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH47 is a Gram-negative bacterium characterized by its spirilla shape and typically found as single cells. This microbe demonstrates a microaerophilic oxygen requirement, indicating its preference for environments with reduced oxygen levels, which is consistent with its association with host habitats. Optimal growth occurs at a temperature of 37.0 °C, aligning with the physiological conditions found in the gastrointestinal tract of mammals, particularly humans. As a host-associated organism, H. pylori str. ZH47 is likely adapted to thrive in the acidic environment of the stomach, where it may play a role in the complex microbial community residing there. The unique morphology of this strain, along with its specific growth requirements, suggests potential adaptations that allow it to colonize and persist in such a challenging niche. Further investigation into its interactions within the host environment may provide insights into its ecological role and its impact on host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH47

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH47
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH47 41, whole genome shotgun sequence.

Gene Summary

Adenine Count

480406 bp

Thymine Count

482096 bp

Guanine Count

307106 bp

Cytosine Count

306888 bp

Genome Length

1579528 bp

Protein-coding Genes

1437 genes

Non-Coding Genes

40 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tryptophan--trna ligaseECC45_06640Not AvailablePositive1317144 - 131816338384.9
abc transporter substrate-binding proteinECC45_06645Not AvailablePositive1318164 - 131994568600.5
microcin c abc transporter permease yejbECC45_06650Not AvailablePositive1319942 - 132098838923.7
sh3 domain-containing proteinECC45_06655Not AvailablePositive1320997 - 132158721822.1
shikimate dehydrogenaseECC45_06660Not AvailablePositive1321595 - 132238629141.6
rnb domain-containing ribonucleaseECC45_06665Not AvailablePositive1322386 - 132432074346.6
hypothetical proteinECC45_06670Not AvailablePositive1324310 - 132533239580.9
30s ribosomal protein s6ECC45_06680Not AvailablePositive1325485 - 132591316994.4
single-stranded dna-binding proteinECC45_06685Not AvailablePositive1325923 - 132646820212.6
30s ribosomal protein s18ECC45_06690Not AvailablePositive1326491 - 132674810448.9

Displaying genes 1261 – 1270 of 1477 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total