Helicobacter pylori str. Zh38

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. Zh38 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, making it well-suited to its host-associated habitat, where it is commonly found in the gastric environment of mammals. As a member of the Helicobacter genus, H. pylori str. Zh38 likely adapts to the harsh conditions of the stomach, including acidic pH levels, through specialized physiological mechanisms. Its microaerophilic nature indicates that it requires reduced levels of oxygen for growth, reflecting its adaptation to the relatively low oxygen concentrations found in the gastric mucosa. The ability to survive and proliferate in this unique niche suggests H. pylori str. Zh38 may play a role in influencing the microbial community structure within the host’s gut environment. Further exploration of this strain could reveal insights into its interactions with host organisms and its potential contributions to the gastric microbiome, as well as its adaptive strategies that allow it to persist in a challenging habitat. Understanding the dynamics of H. pylori str. Zh38 could enhance our knowledge of microbial ecology in host-associated environments and the evolutionary pressures that shape such organisms.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZh38

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. Zh38
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain Zh38 40, whole genome shotgun sequence.

Gene Summary

Adenine Count

476377 bp

Thymine Count

475637 bp

Guanine Count

300937 bp

Cytosine Count

307739 bp

Genome Length

1563685 bp

Protein-coding Genes

1394 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s ribosomal rnaNot AvailableNot AvailablePositive615 - 2121Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive1080 - 3969Not Available
outer membrane beta-barrel protein hofdECC36_00005Not AvailableNegative216 - 166155395.0
outer membrane beta-barrel protein hofcECC36_00010Not AvailableNegative1686 - 327259703.2
catalaseECC36_00015Not AvailablePositive3549 - 449335921.6
5s ribosomal rnaNot AvailableNot AvailablePositive4200 - 4317Not Available
giy-yig nuclease family proteinECC36_00045Not AvailableNegative6865 - 747923238.5
dna adenine methylaseECC36_00050Not AvailableNegative7482 - 841135810.4
translational gtpase typaECC36_00055Not AvailableNegative8427 - 1022666652.4
lipopolysaccharide heptosyltransferase family proteinECC36_00060Not AvailableNegative10272 - 1112033306.3

Displaying genes 1 – 10 of 1436 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
CancerCausesPMC7459201
CancerCausesPMC8032737
GastritisCausesPMC8032737
Gastric ulcerCausesPMC8032737
Duodenal ulcerCausesPMC8032737
Gastric cancerCausesPMC8882093
Chronic gastritisCausesPMC8882093
Atrophic gastritisCausesPMC8882093
Intestinal metaplasiaCausesPMC8882093
DysplasiaCausesPMC8882093

Displaying health effects 41 – 50 of 94 in total