Helicobacter pylori str. Zh38

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. Zh38 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, making it well-suited to its host-associated habitat, where it is commonly found in the gastric environment of mammals. As a member of the Helicobacter genus, H. pylori str. Zh38 likely adapts to the harsh conditions of the stomach, including acidic pH levels, through specialized physiological mechanisms. Its microaerophilic nature indicates that it requires reduced levels of oxygen for growth, reflecting its adaptation to the relatively low oxygen concentrations found in the gastric mucosa. The ability to survive and proliferate in this unique niche suggests H. pylori str. Zh38 may play a role in influencing the microbial community structure within the host’s gut environment. Further exploration of this strain could reveal insights into its interactions with host organisms and its potential contributions to the gastric microbiome, as well as its adaptive strategies that allow it to persist in a challenging habitat. Understanding the dynamics of H. pylori str. Zh38 could enhance our knowledge of microbial ecology in host-associated environments and the evolutionary pressures that shape such organisms.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZh38

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. Zh38
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain Zh38 40, whole genome shotgun sequence.

Gene Summary

Adenine Count

476377 bp

Thymine Count

475637 bp

Guanine Count

300937 bp

Cytosine Count

307739 bp

Genome Length

1563685 bp

Protein-coding Genes

1394 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosomal rna small subunit methyltransferase gECC36_00435Not AvailablePositive84804 - 8534020578.2
prokaryotic metallothionein family proteinECC36_00440Not AvailablePositive85283 - 8557611413.1
hypothetical proteinECC36_00445Not AvailablePositive85579 - 8598615454.8
Trna-serNot AvailableNot AvailablePositive86029 - 86116Not Available
outer membrane proteinECC36_00455Not AvailableNegative86118 - 8672023522.3
two-component system response regulatorECC36_00460Not AvailablePositive87011 - 8738513916.0
50s ribosomal protein l11 methyltransferaseECC36_00465Not AvailablePositive87386 - 8837537617.3
atp-dependent metallopeptidase ftsh/yme1/tma family proteinECC36_00470Not AvailablePositive88384 - 9028269750.4
hypothetical proteinECC36_00475Not AvailablePositive90285 - 9053910109.8
cdp-diacylglycerol--serine o-phosphatidyltransferaseECC36_00480Not AvailablePositive90529 - 9124226649.6

Displaying genes 81 – 90 of 1436 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total