Helicobacter pylori str. Zh38

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. Zh38 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, making it well-suited to its host-associated habitat, where it is commonly found in the gastric environment of mammals. As a member of the Helicobacter genus, H. pylori str. Zh38 likely adapts to the harsh conditions of the stomach, including acidic pH levels, through specialized physiological mechanisms. Its microaerophilic nature indicates that it requires reduced levels of oxygen for growth, reflecting its adaptation to the relatively low oxygen concentrations found in the gastric mucosa. The ability to survive and proliferate in this unique niche suggests H. pylori str. Zh38 may play a role in influencing the microbial community structure within the host’s gut environment. Further exploration of this strain could reveal insights into its interactions with host organisms and its potential contributions to the gastric microbiome, as well as its adaptive strategies that allow it to persist in a challenging habitat. Understanding the dynamics of H. pylori str. Zh38 could enhance our knowledge of microbial ecology in host-associated environments and the evolutionary pressures that shape such organisms.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZh38

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. Zh38
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain Zh38 40, whole genome shotgun sequence.

Gene Summary

Adenine Count

476377 bp

Thymine Count

475637 bp

Guanine Count

300937 bp

Cytosine Count

307739 bp

Genome Length

1563685 bp

Protein-coding Genes

1394 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-argNot AvailableNot AvailablePositive138554 - 138630Not Available
nad+ synthaseECC36_00720Not AvailablePositive138715 - 13949729193.5
tetraacyldisaccharide 4'-kinaseECC36_00725Not AvailablePositive139494 - 14043235483.6
udp-4-amino-4, 6-dideoxy-n-acetyl-beta-l-altrosamine n-acetyltransferaseECC36_00730Not AvailableNegative140365 - 14090721224.5
cmp-n-acetylneuraminic acid synthetaseECC36_00735Not AvailableNegative140904 - 14179733950.1
pseudaminic acid cytidylyltransferaseECC36_00740Not AvailableNegative141767 - 14245025976.2
flagellar basal body l-ring protein flghECC36_00745Not AvailableNegative142468 - 14318126469.2
outer membrane proteinECC36_00750Not AvailablePositive143284 - 14404828933.7
nuclease nuctECC36_00755Not AvailableNegative144055 - 14459720112.5
hypothetical proteinECC36_00760Not AvailablePositive144741 - 14617155441.2

Displaying genes 131 – 140 of 1436 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total