Helicobacter pylori str. ZH106

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH106 is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and occurrence as single cells. This strain thrives optimally at a temperature of 37.0°C, indicating a preference for the warm conditions typically found within a host. As a member of the genus Helicobacter, H. pylori str. ZH106 is notably associated with the gastric environment of its host, where it colonizes the mucosal lining of the stomach. The microaerophilic nature of H. pylori str. ZH106 suggests that it requires reduced levels of oxygen for optimal growth, which aligns with its habitat in the oxygen-limited gastric niche. This adaptation may play a significant role in the bacterium's survival and persistence in the hostile environment of the human stomach, where it can evade immune responses and thrive despite the acidic conditions. Understanding the traits of H. pylori str. ZH106 contributes to our knowledge of microbial adaptation to specific ecological niches, particularly how certain bacteria can exploit host-associated environments for survival and propagation. This highlights the intricate relationships between microbial species and their hosts, particularly in environments that pose significant physiological challenges.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH106

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH106
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH106 41, whole genome shotgun

Gene Summary

Adenine Count

505138 bp

Thymine Count

496690 bp

Guanine Count

324439 bp

Cytosine Count

309253 bp

Genome Length

1638376 bp

Protein-coding Genes

1486 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-hisNot AvailableNot AvailablePositive1427857 - 1427933Not Available
Trna-proNot AvailableNot AvailablePositive1428001 - 1428078Not Available
4-hydroxyphenylacetate catabolism regulator hpaaEC556_07085Not AvailableNegative1428264 - 142901328368.4
neuraminyllactose-binding hemagglutinin-like domain proteinEC556_07090Not AvailableNegative1429000 - 14291405616.75
glutamine-hydrolyzing gmp synthaseEC556_07095Not AvailableNegative1429097 - 143062356795.3
hypothetical proteinEC556_07100Not AvailableNegative1430634 - 143112518902.4
hypothetical proteinEC556_07105Not AvailableNegative1431049 - 14313099849.82
duf3972 domain-containing proteinEC556_07115Not AvailableNegative1433792 - 143438222518.2
aminotransferase class v-fold plp-dependent enzymeEC556_07120Not AvailableNegative1434408 - 143573048618.0
histidine triad nucleotide-binding proteinEC556_07125Not AvailableNegative1435749 - 143606311855.6

Displaying genes 1361 – 1370 of 1528 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total