Helicobacter pylori str. ZH05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH05 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe is known to thrive in a microaerophilic environment, which is indicative of its specialized adaptation to the gastric niche of its host. The optimal growth temperature for H. pylori ZH05 is 37.0°C, aligning with the typical physiological conditions of the human stomach. As a host-associated organism, H. pylori ZH05 resides within the gastric mucosa, where it plays a complex role in the host’s microbiome. The microaerophilic nature of this strain suggests a reliance on low-oxygen conditions, which are prevalent in the gastric environment. This adaptation not only facilitates its survival but may also influence the overall composition of the gastric microbiota. The unique combination of its Gram-negative structure, spirilla morphology, and specific environmental requirements underscores the evolutionary adaptations of H. pylori ZH05. These traits may contribute to its ecological role in the human gastrointestinal tract, where it interacts with both the host and other microbial inhabitants, potentially impacting gastric health and disease dynamics. Further exploration of its interactions and functional capabilities could provide insights into the complexities of gastric microbiome ecology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH05 44, whole genome shotgun sequence.

Gene Summary

Adenine Count

491412 bp

Thymine Count

498593 bp

Guanine Count

309629 bp

Cytosine Count

321632 bp

Genome Length

1624569 bp

Protein-coding Genes

1486 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molybdate abc transporter substrate-binding proteinECB92_03020Not AvailablePositive615861 - 61660127460.6
molybdate abc transporter permease subunitECB92_03025Not AvailablePositive616623 - 61729724825.2
sulfate/molybdate abc transporter atp-binding proteinECB92_03030Not AvailablePositive617294 - 61809130155.8
glutamate--trna ligaseECB92_03035Not AvailableNegative618178 - 61956953377.4
outer membrane proteinECB92_03040Not AvailablePositive619686 - 62054132114.1
outer membrane beta-barrel proteinECB92_03045Not AvailablePositive620542 - 6206564525.5
sulfite exporter taue/safe family proteinECB92_03050Not AvailablePositive620868 - 62170129674.4
hypothetical proteinECB92_03055Not AvailableNegative621678 - 6218847643.59
peptide-methionine (r)-s-oxide reductaseECB92_03060Not AvailableNegative622065 - 62314441200.0
dna repair protein radaECB92_03065Not AvailableNegative623270 - 62461649477.3

Displaying genes 571 – 580 of 1528 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total