Helicobacter pylori str. ZH05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH05 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe is known to thrive in a microaerophilic environment, which is indicative of its specialized adaptation to the gastric niche of its host. The optimal growth temperature for H. pylori ZH05 is 37.0°C, aligning with the typical physiological conditions of the human stomach. As a host-associated organism, H. pylori ZH05 resides within the gastric mucosa, where it plays a complex role in the host’s microbiome. The microaerophilic nature of this strain suggests a reliance on low-oxygen conditions, which are prevalent in the gastric environment. This adaptation not only facilitates its survival but may also influence the overall composition of the gastric microbiota. The unique combination of its Gram-negative structure, spirilla morphology, and specific environmental requirements underscores the evolutionary adaptations of H. pylori ZH05. These traits may contribute to its ecological role in the human gastrointestinal tract, where it interacts with both the host and other microbial inhabitants, potentially impacting gastric health and disease dynamics. Further exploration of its interactions and functional capabilities could provide insights into the complexities of gastric microbiome ecology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH05 44, whole genome shotgun sequence.

Gene Summary

Adenine Count

491412 bp

Thymine Count

498593 bp

Guanine Count

309629 bp

Cytosine Count

321632 bp

Genome Length

1624569 bp

Protein-coding Genes

1486 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rod shape-determining protein mrecECB92_06385Not AvailablePositive1285493 - 128623928169.2
site-specific dna-methyltransferaseECB92_06400Not AvailablePositive1291882 - 129274533512.4
site-specific dna-methyltransferaseECB92_06405Not AvailablePositive1292732 - 129349629717.9
restriction endonuclease subunit rECB92_06410Not AvailablePositive1293531 - 129480250282.4
dna-binding response regulatorECB92_06415Not AvailablePositive1294885 - 129552624901.2
sensor histidine kinaseECB92_06420Not AvailablePositive1295492 - 129669446408.1
nad(p)h-hydrate dehydrataseECB92_06425Not AvailablePositive1296697 - 129809150685.0
replicative dna helicaseECB92_06430Not AvailablePositive1298102 - 129956255467.4
comec family dna internalization-related competence proteinECB92_06435Not AvailablePositive1299643 - 130087247178.2
4-hydroxybenzoate polyprenyltransferaseECB92_06440Not AvailablePositive1300901 - 130178532913.1

Displaying genes 1201 – 1210 of 1528 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total