Helicobacter pylori str. 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to host-associated environments, likely within the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 29CaP suggests that it requires low levels of oxygen for growth, which is consistent with its ecological niche in the acidic environment of the stomach, where oxygen levels are typically reduced. The specific morphology of H. pylori str. 29CaP, combined with its physiological requirements, highlights its specialized adaptations for survival in a highly competitive and hostile habitat. This strain's characteristics may contribute to its ability to persist in the gastric environment, where it can interact with the host's immune response and microbiome. Understanding the traits of H. pylori str. 29CaP can provide insights into its role in gastric health and disease, as well as its ecological dynamics within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 29CaP

Accession NumberNZ_CP012905.1

Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
virb8 family proteinAPV63_RS00205Not Available+37688 - 3843128682.5
trbg/virb9 family p-type conjugative transfer proteinAPV63_RS00210Not Available+38431 - 3940837430.1
dna type iv secretion system protein comb10APV63_RS00215Not Available+39401 - 4053742296.3
mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomeraseAPV63_RS00220P07874+40607 - 4201953258.0
gdp-mannose 4,6-dehydrataseAPV63_RS00225Q56872+42074 - 4321943827.4
gdp-l-fucose synthaseAPV63_RS00230G4WJD3+43212 - 4414434800.4
hydrogenase expression/formation protein hypeAPV63_RS00235P26412-44445 - 4544336453.5
carbamoyltransferase hypfAPV63_RS00240Q55638-45446 - 4769884777.5
agmatine deiminase family proteinAPV63_RS00245Q2SRJ6-47695 - 4868737707.4
site-specific dna-methyltransferaseAPV63_RS00250P50178-48739 - 4943727093.0

Displaying genes 41 – 50 of 1556 in total

Pathways

26 pathways

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0010884(7R,8S)-7,8-diammoniononanoateC9H21N2O2Chemical structure of (7R,8S)-7,8-diammoniononanoateNot available
Average189.278Da
Monoisotopic189.1597543Da
BASm0010887(4R,5S)-dethiobiotinC10H18N2O3Chemical structure of (4R,5S)-dethiobiotin533-48-2
Average214.2615Da
Monoisotopic214.1317425Da
BASm0011787(S)-2-hydroxymethylglutarateC6H8O5Chemical structure of (S)-2-hydroxymethylglutarateNot available
Average160.126Da
Monoisotopic160.038270517Da
BASm0012597(6R)-10-formyltetrahydrofolateC20H21N7O7Chemical structure of (6R)-10-formyltetrahydrofolateNot available
Average471.431Da
Monoisotopic471.151343204Da

Displaying 91–94 of 94 metabolites