Helicobacter pylori str. 26083

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 26083 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism predominantly inhabits the gastric mucosa of its host, indicating a strong association with a specific biological niche. Optimal growth conditions for H. pylori strain 26083 are observed at 37.0°C, which aligns with the human body temperature, further emphasizing its adaptation to the host environment. The microaerophilic nature of H. pylori strain 26083 suggests that it thrives in conditions with reduced oxygen levels, which are typically found in the stomach's antrum. This adaptation enables the bacterium to exploit the unique chemical environment of the gastric lining, where it can evade the host's immune response and establish a persistent presence. The morphology and cellular arrangement of H. pylori strain 26083 are significant for its motility, allowing it to navigate through the viscous gastric mucus. In summary, H. pylori strain 26083 exemplifies the specialized adaptations of gastric pathogens to their host environments, particularly through its unique morphology, growth temperature, and oxygen requirements. Understanding these traits provides insight into the ecological dynamics of H. pylori within the gastric niche, highlighting its role in the complex interactions between host and microbe.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain26083

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 26083
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26083 contig_9, whole genome shotgun

Gene Summary

Adenine Count

508528 bp

Thymine Count

510074 bp

Guanine Count

323787 bp

Cytosine Count

324378 bp

Genome Length

1666814 bp

Protein-coding Genes

1477 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar basal body-associated protein flilBB387_00205Not AvailablePositive35764 - 3631520365.8
holo-acp synthaseBB387_00210Not AvailablePositive36322 - 3667812936.9
ligand-gated channelBB387_00215Not AvailablePositive36885 - 3926389601.4
metalloproteaseBB387_00220Not AvailableNegative39274 - 3989423965.5
lipooligosaccharide 5g8 epitope biosynthesis-associated protein (lex2b)BB387_00225Not AvailablePositive39976 - 4083633259.8
bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase iiBB387_00230Not AvailablePositive41013 - 4204738935.1
ubiquitin--protein ligaseBB387_00235Not AvailablePositive42134 - 4297332153.9
gtp cyclohydrolase iiBB387_00240Not AvailablePositive43062 - 4364021711.2
molybdopterin synthase sulfur carrier subunitBB387_00245Not AvailablePositive43715 - 439368106.9
molybdenum cofactor biosynthesis protein moaeBB387_00250Not AvailablePositive43937 - 4437416525.2

Displaying genes 41 – 50 of 1520 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total