Helicobacter pylori str. 22343

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22343 is a Gram-negative bacterium characterized by its unique spirilla shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically residing in the gastric mucosa of mammals. H. pylori strain 22343 exhibits microaerophilic characteristics, indicating that it requires lower levels of oxygen than are present in the atmosphere for optimal growth. The microaerophilic nature of H. pylori suggests that it is well-adapted to the gastric environment, where oxygen levels are significantly reduced compared to ambient conditions. This adaptation plays a crucial role in its survival and potential interaction with the host's immune system. Understanding the specific growth conditions and environmental preferences of H. pylori strain 22343 can provide insights into its ecological niche within the host and its potential influence on gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22343

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22343
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22343 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

535227 bp

Thymine Count

539188 bp

Guanine Count

344275 bp

Cytosine Count

341653 bp

Genome Length

1760343 bp

Protein-coding Genes

1534 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiol:disulfide interchange proteinBB414_01470Not AvailablePositive725201 - 72587225535.3
cytochrome c biogenesis proteinBB414_01475Not AvailablePositive725882 - 728692106223.0
fucosyltransferaseBB414_01480Not AvailablePositive728702 - 73001551005.3
glutamate dehydrogenaseBB414_01485Not AvailableNegative730030 - 73137649439.3
protein-(glutamine-n5) methyltransferase, release factor-specificBB414_01490Not AvailableNegative731443 - 73227331480.4
peptidase m48BB414_01495Not AvailableNegative732270 - 73349346306.6
hypothetical proteinBB414_01500Not AvailablePositive733674 - 73419819878.6
sporulation proteinBB414_01505Not AvailableNegative734201 - 73494728785.3
duf904 domain-containing proteinBB414_01510Not AvailablePositive735148 - 7353758460.06
hypothetical proteinBB414_01515Not AvailablePositive735388 - 7356249277.99

Displaying genes 651 – 660 of 1576 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total