Helicobacter pylori str. 22343

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22343 is a Gram-negative bacterium characterized by its unique spirilla shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically residing in the gastric mucosa of mammals. H. pylori strain 22343 exhibits microaerophilic characteristics, indicating that it requires lower levels of oxygen than are present in the atmosphere for optimal growth. The microaerophilic nature of H. pylori suggests that it is well-adapted to the gastric environment, where oxygen levels are significantly reduced compared to ambient conditions. This adaptation plays a crucial role in its survival and potential interaction with the host's immune system. Understanding the specific growth conditions and environmental preferences of H. pylori strain 22343 can provide insights into its ecological niche within the host and its potential influence on gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22343

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22343
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22343 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

535227 bp

Thymine Count

539188 bp

Guanine Count

344275 bp

Cytosine Count

341653 bp

Genome Length

1760343 bp

Protein-coding Genes

1534 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
excinuclease abc subunit aBB414_00845Not AvailablePositive149913 - 152720104058.0
hypothetical proteinBB414_00850Not AvailableNegative153405 - 15381215937.4
aaa family atpaseBB414_00860Not AvailableNegative154397 - 15554243479.0
hypothetical proteinBB414_00865Not AvailableNegative155539 - 15601218149.2
dna gyrase subunit aBB414_00870Not AvailableNegative156012 - 15849592823.1
diacylglycerol kinaseBB414_00875Not AvailableNegative158511 - 15889714454.9
hypothetical proteinBB414_00880Not AvailableNegative158890 - 15990338431.5
acetone carboxylase subunit gammaBB414_00890Not AvailableNegative160317 - 16081719694.6
acetone carboxylase subunit alphaBB414_00895Not AvailableNegative160834 - 16313186462.5
hypothetical proteinBB414_00905Not AvailableNegative165517 - 16651838532.1

Displaying genes 171 – 180 of 1576 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total