Helicobacter pylori str. 22316

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22316 is a Gram-negative, microaerophilic bacterium characterized by its distinctive spirilla shape and singular cell arrangement. This organism thrives optimally at a temperature of 37.0°C, indicating its adaptation to the human gastric environment, where it is primarily found as a host-associated microbe. H. pylori is known for its ability to colonize the gastric epithelium, and its microaerophilic nature suggests that it requires lower levels of oxygen for optimal growth compared to aerobic organisms. This adaptation is crucial for survival in the acidic conditions of the stomach, where it can play a role in the complex interactions within the gastrointestinal microbiome. The unique morphology and physiological traits of H. pylori strain 22316 exemplify the intricate relationship between microbial life and host physiology, highlighting the importance of environmental conditions in shaping microbial behavior and ecological niches. Understanding the specific adaptations of H. pylori may provide insights into its role in gastric health and disease, as well as its interactions with the host immune system.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22316

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22316
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22316 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

584409 bp

Thymine Count

568954 bp

Guanine Count

367632 bp

Cytosine Count

366447 bp

Genome Length

1887442 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB424_03650Not AvailablePositive350624 - 35259773074.8
competence protein comgfBB424_03655Not AvailablePositive352788 - 35400847228.1
rna polymerase factor sigma-54BB424_03660Not AvailableNegative354120 - 35536448233.2
lps export abc transporter atp-binding proteinBB424_03665Not AvailableNegative355367 - 35608926443.1
trna (n6-adenosine(37)-n6)-threonylcarbamoyltransferase complex atpase tsaeBB424_03670Not AvailableNegative356102 - 35650315052.6
dna polymerase iii subunit gamma/tauBB424_03675Not AvailableNegative356500 - 35825766726.2
lysine transporterBB424_03680Not AvailableNegative358326 - 35895823215.6
hypothetical proteinBB424_03685Not AvailablePositive359217 - 35963916035.6
zinc abc transporter substrate-binding proteinBB424_03690Not AvailablePositive359668 - 36012917603.1
hypothetical proteinBB424_03695Not AvailablePositive360310 - 36072915523.6

Displaying genes 331 – 340 of 1617 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total