Helicobacter pylori str. 22151

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22151 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives in host-associated habitats, indicating a strong association with animal hosts, particularly in the gastrointestinal tract of humans. The optimal growth temperature for H. pylori str. 22151 is 37.0°C, which aligns with the typical body temperature of its mammalian hosts, suggesting an adaptation to survive and proliferate in this specific environment. H. pylori is notable for its ability to colonize the gastric epithelium, where it can influence local microenvironments. Its microaerophilic nature implies an adaptation to low oxygen levels, which is often encountered in the gastric niche where it resides. The physiological traits of this strain underscore its potential role in gastrointestinal dynamics and its capability to interact with host immune responses. Furthermore, the solitary arrangement of H. pylori str. 22151 may provide advantages in nutrient acquisition and colonization strategies, as individual cells can effectively navigate the complex gastric environment without the constraints of larger aggregates. Understanding the specific traits of this strain can contribute to broader insights into the ecological role of H. pylori within its host and the implications for host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22151

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22151
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22151 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

508905 bp

Thymine Count

514509 bp

Guanine Count

328731 bp

Cytosine Count

321911 bp

Genome Length

1674056 bp

Protein-coding Genes

1493 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporterBB432_04340Not AvailablePositive1437262 - 143780421225.7
hypothetical proteinBB432_04345Not AvailablePositive1437826 - 143863830685.9
hypothetical proteinBB432_04350Not AvailableNegative1439034 - 144028148179.3
hypothetical proteinBB432_04355Not AvailableNegative1440278 - 144056511106.4
tigr00645 family proteinBB432_04365Not AvailablePositive1440884 - 144141719856.9
hypothetical proteinBB432_04370Not AvailableNegative1441423 - 144293158189.2
fumarate reductaseBB432_04375Not AvailableNegative1442948 - 144368527612.3
fumarate reductase flavoprotein subunitBB432_04380Not AvailableNegative1443678 - 144582280160.9
fumarate reductaseBB432_04385Not AvailableNegative1445832 - 144659928861.8
triose-phosphate isomeraseBB432_04390Not AvailablePositive1446814 - 144751826616.4

Displaying genes 1311 – 1320 of 1535 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total