Helicobacter pylori str. 22151

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22151 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives in host-associated habitats, indicating a strong association with animal hosts, particularly in the gastrointestinal tract of humans. The optimal growth temperature for H. pylori str. 22151 is 37.0°C, which aligns with the typical body temperature of its mammalian hosts, suggesting an adaptation to survive and proliferate in this specific environment. H. pylori is notable for its ability to colonize the gastric epithelium, where it can influence local microenvironments. Its microaerophilic nature implies an adaptation to low oxygen levels, which is often encountered in the gastric niche where it resides. The physiological traits of this strain underscore its potential role in gastrointestinal dynamics and its capability to interact with host immune responses. Furthermore, the solitary arrangement of H. pylori str. 22151 may provide advantages in nutrient acquisition and colonization strategies, as individual cells can effectively navigate the complex gastric environment without the constraints of larger aggregates. Understanding the specific traits of this strain can contribute to broader insights into the ecological role of H. pylori within its host and the implications for host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22151

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22151
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22151 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

508905 bp

Thymine Count

514509 bp

Guanine Count

328731 bp

Cytosine Count

321911 bp

Genome Length

1674056 bp

Protein-coding Genes

1493 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chemotaxis protein chewBB432_03990Not AvailableNegative1366096 - 136659318981.9
chemotaxis protein cheaBB432_03995Not AvailableNegative1366590 - 136901690249.4
fused signal transduction protein/response regulatorBB432_04000Not AvailableNegative1369072 - 137000735563.9
udp-2,3-diacylglucosamine hydrolaseBB432_04005Not AvailableNegative1370011 - 137076929525.8
yggs family pyridoxal phosphate enzymeBB432_04010Not AvailableNegative1370771 - 137143925127.9
menaquinone biosynthesis decarboxylaseBB432_04015Not AvailableNegative1371462 - 137331271047.6
phosphoglycerate dehydrogenaseBB432_04020Not AvailableNegative1373322 - 137489657860.6
hypothetical proteinBB432_04025Not AvailableNegative1374912 - 137544520678.3
30s ribosomal protein s1BB432_04030Not AvailableNegative1375474 - 137714462882.2
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseBB432_04035Not AvailableNegative1377265 - 137808930932.7

Displaying genes 1241 – 1250 of 1535 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total