Helicobacter pylori str. 22151

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22151 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives in host-associated habitats, indicating a strong association with animal hosts, particularly in the gastrointestinal tract of humans. The optimal growth temperature for H. pylori str. 22151 is 37.0°C, which aligns with the typical body temperature of its mammalian hosts, suggesting an adaptation to survive and proliferate in this specific environment. H. pylori is notable for its ability to colonize the gastric epithelium, where it can influence local microenvironments. Its microaerophilic nature implies an adaptation to low oxygen levels, which is often encountered in the gastric niche where it resides. The physiological traits of this strain underscore its potential role in gastrointestinal dynamics and its capability to interact with host immune responses. Furthermore, the solitary arrangement of H. pylori str. 22151 may provide advantages in nutrient acquisition and colonization strategies, as individual cells can effectively navigate the complex gastric environment without the constraints of larger aggregates. Understanding the specific traits of this strain can contribute to broader insights into the ecological role of H. pylori within its host and the implications for host health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22151

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22151
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22151 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

508905 bp

Thymine Count

514509 bp

Guanine Count

328731 bp

Cytosine Count

321911 bp

Genome Length

1674056 bp

Protein-coding Genes

1493 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
diguanylate cyclaseBB432_03675Not AvailablePositive1308183 - 130904030911.0
peptide abc transporter atp-binding proteinBB432_03680Not AvailablePositive1309052 - 130991532385.8
abc transporter atp-binding proteinBB432_03685Not AvailablePositive1309912 - 131071830406.3
gtpase obgeBB432_03690Not AvailablePositive1310738 - 131182038787.8
alginate lyaseBB432_03695Not AvailablePositive1311857 - 131285237664.7
polyisoprenoid-binding proteinBB432_03700Not AvailablePositive1313117 - 131367120385.9
glutamate-1-semialdehyde-2,1-aminomutaseBB432_03705Not AvailablePositive1313681 - 131497346746.2
arginine biosynthesis protein argjBB432_03710Not AvailablePositive1314979 - 131524210060.5
hypothetical proteinBB432_03715Not AvailablePositive1315258 - 131566215030.8
n-carbomoyl-d-amino acid amidohydrolaseBB432_03720Not AvailablePositive1315746 - 131662432509.4

Displaying genes 1181 – 1190 of 1535 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total