Helicobacter pylori str. 22023

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22023 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at 37.0°C, a temperature consistent with the physiological conditions of its typical host environments. H. pylori is primarily found in association with the gastric mucosa of mammals, highlighting its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori requires reduced levels of oxygen for growth, which aligns with its niche in the gastric environment where oxygen concentrations are lower than in atmospheric conditions. The unique morphology and growth requirements of strain 22023 may play a role in its survival and colonization within the harsh gastric environment, potentially influencing its interactions with host immune responses. Understanding the physiological traits of H. pylori strain 22023 can provide insights into its ecological niche and its potential roles in gastrointestinal microbiomes. Given its adaptation to a microaerophilic lifestyle and optimal growth temperature, further studies may explore how these traits contribute to its metabolic pathways and interactions with the host, which could be pivotal in understanding the broader implications of H. pylori in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22023

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22023
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22023 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

493186 bp

Thymine Count

494318 bp

Guanine Count

319828 bp

Cytosine Count

311499 bp

Genome Length

1618831 bp

Protein-coding Genes

1439 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenylosuccinate synthaseBB438_01435Not AvailablePositive279245 - 28048045862.4
flagellar flij family proteinBB438_01440Not AvailablePositive280477 - 28090516658.2
flagellar proteinBB438_01445Not AvailablePositive280898 - 28155724896.2
rip metalloprotease rsepBB438_01450Not AvailablePositive281554 - 28260338459.4
exodeoxyribonuclease vii large subunitBB438_01455Not AvailablePositive282616 - 28387847158.2
dna methyltransferaseBB438_01460Not AvailableNegative283897 - 28505144638.1
hypothetical proteinBB438_01465Not AvailableNegative285062 - 28546015780.7
hypothetical proteinBB438_01470Not AvailablePositive285650 - 28625823734.2
dna methyltransferaseBB438_01475Not AvailablePositive286332 - 28709029235.8
atp-dependent chaperone clpbBB438_01480Not AvailablePositive287163 - 28973396675.3

Displaying genes 271 – 280 of 1481 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total