Helicobacter pylori str. 22023

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22023 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at 37.0°C, a temperature consistent with the physiological conditions of its typical host environments. H. pylori is primarily found in association with the gastric mucosa of mammals, highlighting its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori requires reduced levels of oxygen for growth, which aligns with its niche in the gastric environment where oxygen concentrations are lower than in atmospheric conditions. The unique morphology and growth requirements of strain 22023 may play a role in its survival and colonization within the harsh gastric environment, potentially influencing its interactions with host immune responses. Understanding the physiological traits of H. pylori strain 22023 can provide insights into its ecological niche and its potential roles in gastrointestinal microbiomes. Given its adaptation to a microaerophilic lifestyle and optimal growth temperature, further studies may explore how these traits contribute to its metabolic pathways and interactions with the host, which could be pivotal in understanding the broader implications of H. pylori in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22023

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22023
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22023 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

493186 bp

Thymine Count

494318 bp

Guanine Count

319828 bp

Cytosine Count

311499 bp

Genome Length

1618831 bp

Protein-coding Genes

1439 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-seryl-trna(sec) selenium transferaseBB438_03045Not AvailableNegative1092598 - 109375843755.3
tonb-dependent receptorBB438_03050Not AvailableNegative1093979 - 109661897571.2
iron-regulated proteinBB438_03055Not AvailableNegative1096788 - 109711412517.2
dihydroneopterin aldolaseBB438_03060Not AvailableNegative1097098 - 109745113859.9
glycerol-3-phosphate acyltransferaseBB438_03065Not AvailableNegative1097448 - 109811023874.4
cytochrome c oxidase accessory protein ccogBB438_03070Not AvailablePositive1098216 - 109959252745.2
saccharopine dehydrogenaseBB438_03075Not AvailableNegative1099602 - 110080145225.6
sodium/glutamate symporterBB438_03080Not AvailablePositive1100887 - 110211343904.0
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductaseBB438_03085Not AvailablePositive1102110 - 110314438866.4
methyltransferaseBB438_03090Not AvailablePositive1103126 - 110384226680.5

Displaying genes 1001 – 1010 of 1481 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total