Helicobacter pylori str. 1846/05

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1846/05 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives at an optimal temperature of 37.0°C, which aligns with the physiological conditions of a mammalian host, suggesting its adaptation to a host-associated habitat. H. pylori is known for its ability to colonize the gastric mucosa, where it can influence local microbial communities and interact with host immune responses. The microaerophilic nature of this strain indicates a preference for environments with reduced oxygen levels, which is consistent with its niche in the stomach, where oxygen availability is limited. This adaptation may play a crucial role in its survival and persistence in such a hostile environment, allowing it to evade immune detection. Understanding the specific traits of H. pylori strain 1846/05 can provide insights into its ecological interactions within the gastric ecosystem. The unique combination of its morphology, oxygen requirements, and optimal growth temperature suggests a finely tuned adaptation to the gastric niche, highlighting the complexity of microbial life and its capacity to thrive in specialized habitats. Further research into this strain may reveal additional insights into its role within the gastric microbiome and its interactions with host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1846/05

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1846/05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1846/05 Contig58, whole genome shotgun

Gene Summary

Adenine Count

499644 bp

Thymine Count

502517 bp

Guanine Count

322326 bp

Cytosine Count

317342 bp

Genome Length

1642077 bp

Protein-coding Genes

1468 genes

Non-Coding Genes

75 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cvpa family proteinHPY1846_00455Not AvailableNegative82990 - 8370026233.4
apolipoprotein acyltransferaseHPY1846_00460Not AvailablePositive83937 - 8522048888.9
abc transporter atp-binding proteinHPY1846_00465Not AvailablePositive85217 - 8585823470.7
n-acetylneuraminate synthaseHPY1846_00470Not AvailablePositive85863 - 8670831500.1
hypothetical proteinHPY1846_00475Not AvailableNegative86819 - 8759829384.4
peptidylprolyl isomeraseHPY1846_00480Not AvailablePositive87722 - 8821017510.8
carbon storage regulatorHPY1846_00485Not AvailablePositive88230 - 884608426.38
4-diphosphocytidyl-2c-methyl-d-erythritol kinaseHPY1846_00490Not AvailablePositive88457 - 8928130932.1
single-stranded dna-binding proteinHPY1846_00495Not AvailablePositive89259 - 8971717825.1
biopolymer transporter exbbHPY1846_00500Not AvailablePositive89723 - 9017516624.9

Displaying genes 121 – 130 of 1547 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total