Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
magnesium transporterHPY1198_00200Not Available+46505 - 4746137167.7
membrane proteinHPY1198_00205Not Available+47468 - 4819627082.6
transposaseHPY1198_00210Not Available-48407 - 4955544942.1
transposaseHPY1198_00215Not Available-49524 - 4999118102.1
membrane proteinHPY1198_00220Not Available-50273 - 5236075808.9
sulfate permeaseHPY1198_00225Not Available+52614 - 5377141495.9
Trna-asnNot AvailableNot Available+53806 - 53880Not Available
membrane proteinHPY1198_00235Not Available-54009 - 5546052905.0
3-deoxy-manno-octulosonate cytidylyltransferaseHPY1198_00240Not Available-55654 - 5638527604.8
disulfide isomeraseHPY1198_00245Not Available+56495 - 5729229530.9

Displaying genes 41 – 50 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0010825N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamideC8H13N2O9PChemical structure of N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamideNot available
Average312.172Da
Monoisotopic312.0369642Da
BASm00108262-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidineC8H15N3O8PChemical structure of 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidineNot available
Average312.195Da
Monoisotopic312.060225Da
BASm0011334(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoAC32H46N7O19P3SChemical structure of (3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoANot available
Average957.73Da
Monoisotopic957.180398777Da
BASm0011336(5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoAC32H44N7O19P3SChemical structure of (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoANot available
Average955.72Da
Monoisotopic955.164748712Da
BASm0012597(6R)-10-formyltetrahydrofolateC20H21N7O7Chemical structure of (6R)-10-formyltetrahydrofolateNot available
Average471.431Da
Monoisotopic471.151343204Da

Displaying 131–135 of 135 metabolites