Helicobacter pylori str. 1198/04

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1198/04 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical human body temperature, suggesting its adaptation to a host-associated habitat. H. pylori is primarily known for colonizing the gastric epithelium, where it is believed to play a role in various gastrointestinal disorders. The microaerophilic nature of H. pylori indicates that it requires reduced levels of oxygen for growth, which is consistent with its ecological niche within the acidic environment of the stomach. This adaptation not only enables the bacterium to survive but also allows it to exploit the unique conditions present in the gastric milieu, where it can evade the host's immune responses and establish colonization. Given these traits, H. pylori strain 1198/04 exemplifies the specialized adaptations of bacteria to their host environments, highlighting the intricate relationships between microbial life and host physiology. Such adaptations may influence microbial diversity and stability within the gastrointestinal tract, potentially affecting overall host health and disease states.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. 1198/04

Accession NumberJSXT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1485 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
quinolinate synthetaseHPY1198_00150Not Available+34799 - 3580937753.7
nicotinate-nucleotide pyrophosphorylaseHPY1198_00155Not Available+35809 - 3663030837.4
dna methyltransferaseHPY1198_00160Not Available+36655 - 3904592786.2
dna methyltransferaseHPY1198_00165Not Available+39173 - 4000932089.1
peptidase s41HPY1198_00170Not Available+40255 - 4161949962.8
periplasmic proteinHPY1198_00175Not Available+41626 - 4278944164.3
acyl-phosphate glycerol 3-phosphate acyltransferaseHPY1198_00180Not Available+42776 - 4348627175.2
uracil-dna glycosylaseHPY1198_00185Not Available+43483 - 4418426252.2
glyceraldehyde-3-phosphate dehydrogenaseHPY1198_00190Not Available+44273 - 4526536071.4
phosphoglycerate kinaseHPY1198_00195Not Available+45281 - 4648944719.2

Displaying genes 31 – 40 of 1526 in total

Pathways

26 pathways

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0002909O-acetyl-L-homoserineC6H11NO4Chemical structure of O-acetyl-L-homoserine7540-67-2
Average161.1558Da
Monoisotopic161.0688078Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm00029834-CDP-2-C-methyl-D-erythritolC14H23N3O14P2Chemical structure of 4-CDP-2-C-methyl-D-erythritolNot available
Average519.294Da
Monoisotopic519.0666236Da
BASm00030584-CDP-2-C-methyl-D-erythritol 2-phosphateC14H22N3O17P3Chemical structure of 4-CDP-2-C-methyl-D-erythritol 2-phosphateNot available
Average597.257Da
Monoisotopic597.0184016Da
BASm0003187N-succinyl-(2S,6S)-2,6-diaminoheptanedioateC11H16N2O7Chemical structure of N-succinyl-(2S,6S)-2,6-diaminoheptanedioateNot available
Average288.257Da
Monoisotopic288.096848Da
BASm0003208L-2-acetamido-6-oxoheptanedioateC9H11NO6Chemical structure of L-2-acetamido-6-oxoheptanedioateNot available
Average229.189Da
Monoisotopic229.059734238Da
BASm0003276S-(5-deoxy-D-ribos-5-yl)-L-homocysteineC9H17NO6SChemical structure of S-(5-deoxy-D-ribos-5-yl)-L-homocysteine15912-98-8
Average267.299Da
Monoisotopic267.077658Da
BASm00032855-methyltetrahydropteroyltri-L-glutamateC30H35N9O12Chemical structure of 5-methyltetrahydropteroyltri-L-glutamateNot available
Average713.663Da
Monoisotopic713.2427119Da

Displaying 41–50 of 135 metabolites