Helicobacter pylori str. ZH34

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH34 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe thrives optimally at 37.0°C, which is indicative of its adaptation to the warm environment of its host. H. pylori str. ZH34 is microaerophilic, meaning it requires reduced levels of oxygen for growth, aligning with its habitat as a host-associated organism. The microbe's spiral morphology may facilitate its motility through the viscous mucus layer of the gastric epithelium, potentially influencing its colonization dynamics within the host. The specific ecological niche occupied by H. pylori str. ZH34 suggests a close relationship with the gastric environment, which could provide insights into its interactions with the host's immune system and its role in gastric health. Understanding these traits can contribute to broader discussions on the microbial communities present in the gastrointestinal tract and their implications for host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH34

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH34
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH34 28, whole genome shotgun sequence.

Gene Summary

Adenine Count

486013 bp

Thymine Count

485362 bp

Guanine Count

310804 bp

Cytosine Count

309669 bp

Genome Length

1593919 bp

Protein-coding Genes

1454 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphatase pap2 family proteinECC32_01930Not AvailableNegative392338 - 39300024740.3
undecaprenyl/decaprenyl-phosphate alpha-n-acetylglucosaminyl 1-phosphate transferaseECC32_01935Not AvailableNegative392931 - 39394137630.8
pyridoxine 5'-phosphate synthaseECC32_01940Not AvailablePositive394077 - 39486529765.4
4-hydroxythreonine-4-phosphate dehydrogenaseECC32_01945Not AvailablePositive394867 - 39579033728.9
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex transferase subunit tsadECC32_01950Not AvailablePositive395854 - 39687637780.9
flagellar basal-body rod protein flggECC32_01955Not AvailablePositive397712 - 39850028063.0
duf3944 domain-containing proteinECC32_01965Not AvailableNegative398594 - 39949033216.2
duf3944 domain-containing proteinECC32_01970Not AvailableNegative400063 - 40082428477.2
duf3944 domain-containing proteinECC32_01980Not AvailableNegative401497 - 40182312623.8
n utilization substance protein bECC32_01985Not AvailableNegative401940 - 40235615520.0

Displaying genes 371 – 380 of 1496 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total