Helicobacter pylori str. ZH34

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH34 is a Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This microbe thrives optimally at 37.0°C, which is indicative of its adaptation to the warm environment of its host. H. pylori str. ZH34 is microaerophilic, meaning it requires reduced levels of oxygen for growth, aligning with its habitat as a host-associated organism. The microbe's spiral morphology may facilitate its motility through the viscous mucus layer of the gastric epithelium, potentially influencing its colonization dynamics within the host. The specific ecological niche occupied by H. pylori str. ZH34 suggests a close relationship with the gastric environment, which could provide insights into its interactions with the host's immune system and its role in gastric health. Understanding these traits can contribute to broader discussions on the microbial communities present in the gastrointestinal tract and their implications for host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH34

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH34
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH34 28, whole genome shotgun sequence.

Gene Summary

Adenine Count

486013 bp

Thymine Count

485362 bp

Guanine Count

310804 bp

Cytosine Count

309669 bp

Genome Length

1593919 bp

Protein-coding Genes

1454 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl-coa carboxylase biotin carboxyl carrier proteinECC32_01100Not AvailableNegative217579 - 21806117591.5
dctp deaminaseECC32_01105Not AvailablePositive218181 - 21874720889.2
hypothetical proteinECC32_01110Not AvailablePositive218907 - 22101578097.4
16s rrna (uracil(1498)-n(3))-methyltransferaseECC32_01115Not AvailableNegative221100 - 22178025783.5
hypothetical proteinECC32_01120Not AvailableNegative221781 - 22221216417.2
ferrochelataseECC32_01125Not AvailablePositive222268 - 22327238792.3
thiol:disulfide interchange proteinECC32_01130Not AvailablePositive223349 - 22401425346.1
cytochrome c biogenesis proteinECC32_01135Not AvailablePositive224024 - 226834106247.0
fucosyltransferaseECC32_01140Not AvailablePositive226844 - 2270387562.18
hypothetical proteinECC32_01145Not AvailableNegative227039 - 22781829261.1

Displaying genes 211 – 220 of 1496 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total