Helicobacter pylori str. ZH138

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH138 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives in microaerophilic environments, indicating that it requires reduced oxygen levels for optimal growth. The optimal temperature for strain ZH138 is 37.0°C, suggesting a preference for conditions similar to those found in the human gastrointestinal tract, where it is typically host-associated. As a member of the Helicobacter genus, H. pylori is well-known for its adaptation to the acidic environment of the stomach. The microaerophilic nature of strain ZH138 may offer insights into its metabolic pathways and survival strategies in low-oxygen environments. Understanding the specific adaptations of this strain, such as its enzymatic capabilities and potential interactions with the host immune system, can provide valuable information about its role within the gastrointestinal ecosystem. This strain exemplifies the complexity of microbial life in host-associated environments, demonstrating how specific physiological traits can influence the ecological niches that bacteria occupy. Further research may elucidate the unique interactions of H. pylori strain ZH138 with its host and its potential implications for gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH138

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH138
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH138 297, whole genome shotgun

Gene Summary

Adenine Count

512789 bp

Thymine Count

510599 bp

Guanine Count

330043 bp

Cytosine Count

326750 bp

Genome Length

1701155 bp

Protein-coding Genes

1709 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transketolaseEDB75_02880Not AvailableNegative586143 - 58806870623.7
bifunctional riboflavin kinase/fad synthetaseEDB75_02885Not AvailableNegative588115 - 58895732291.9
tlya family rna methyltransferaseEDB75_02890Not AvailableNegative588923 - 58963026570.6
hypothetical proteinEDB75_02895Not AvailableNegative589630 - 59014519691.4
aspartate carbamoyltransferaseEDB75_02900Not AvailablePositive590212 - 59113534064.6
outer membrane beta-barrel protein hofbEDB75_02905Not AvailablePositive591392 - 59283153022.8
abc transporter atp-binding proteinEDB75_02910Not AvailablePositive592922 - 59457761858.2
neuraminyllactose-binding hemagglutinin family proteinEDB75_02915Not AvailablePositive594571 - 59500716604.4
type i restriction endonuclease subunit rEDB75_02920Not AvailablePositive595008 - 59740793800.4
m48 family peptidaseEDB75_02925Not AvailablePositive597407 - 59811428136.4

Displaying genes 541 – 550 of 1753 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total