Helicobacter pylori str. ZH138

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH138 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives in microaerophilic environments, indicating that it requires reduced oxygen levels for optimal growth. The optimal temperature for strain ZH138 is 37.0°C, suggesting a preference for conditions similar to those found in the human gastrointestinal tract, where it is typically host-associated. As a member of the Helicobacter genus, H. pylori is well-known for its adaptation to the acidic environment of the stomach. The microaerophilic nature of strain ZH138 may offer insights into its metabolic pathways and survival strategies in low-oxygen environments. Understanding the specific adaptations of this strain, such as its enzymatic capabilities and potential interactions with the host immune system, can provide valuable information about its role within the gastrointestinal ecosystem. This strain exemplifies the complexity of microbial life in host-associated environments, demonstrating how specific physiological traits can influence the ecological niches that bacteria occupy. Further research may elucidate the unique interactions of H. pylori strain ZH138 with its host and its potential implications for gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH138

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH138
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH138 297, whole genome shotgun

Gene Summary

Adenine Count

512789 bp

Thymine Count

510599 bp

Guanine Count

330043 bp

Cytosine Count

326750 bp

Genome Length

1701155 bp

Protein-coding Genes

1709 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
beta-ketoacyl-acp synthase iiEDB75_01315Not AvailablePositive277015 - 27825343611.4
acetyl-coa carboxylase carboxyl transferase subunit alphaEDB75_01320Not AvailablePositive278276 - 27921434867.2
hypothetical proteinEDB75_01325Not AvailablePositive279680 - 28011716881.8
hypothetical proteinEDB75_01330Not AvailableNegative280189 - 28101031351.3
sialidaseEDB75_01335Not AvailableNegative281007 - 28197236897.9
23s rrna (guanosine(2251)-2'-o)-methyltransferase rlmbEDB75_01340Not AvailableNegative281985 - 28266824811.9
16s rrna (cytidine(1402)-2'-o)-methyltransferaseEDB75_01345Not AvailableNegative282681 - 28354432792.0
50s ribosomal protein l31EDB75_01350Not AvailableNegative283569 - 2837727652.32
transcription termination factor rhoEDB75_01355Not AvailablePositive284037 - 28535349575.6
glutamate racemaseEDB75_01360Not AvailablePositive285391 - 28615828462.0

Displaying genes 261 – 270 of 1753 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total