Helicobacter pylori str. ZH134

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH134 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives at an optimal temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically found in the gastric mucosa of mammals. The microaerophilic nature of H. pylori indicates that it requires reduced oxygen levels for optimal growth, which is consistent with its ecological niche within the stomach, where oxygen availability is limited. The unique spiral morphology of H. pylori contributes to its motility within the viscous gastric environment, allowing it to navigate through mucus layers and adhere to the epithelial cells. This adaptation is crucial for its survival and potential interactions with the host's immune system. Understanding the specific growth conditions and morphological traits of H. pylori strain ZH134 can provide insights into its role in the gastric ecosystem, as well as its interactions with host physiology. Further research may elucidate the microbial dynamics and host responses associated with this strain, potentially revealing its significance in health and disease contexts.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH134

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH134
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH134 191, whole genome shotgun

Gene Summary

Adenine Count

503318 bp

Thymine Count

503543 bp

Guanine Count

323683 bp

Cytosine Count

317830 bp

Genome Length

1661632 bp

Protein-coding Genes

1598 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hugz family heme oxygenaseEC600_00005Not AvailablePositive1 - 1726266.55
5s ribosomal rnaNot AvailableNot AvailablePositive48 - 165Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive400 - 3287Not Available
16s ribosomal rnaNot AvailableNot AvailablePositive495 - 2003Not Available
ybfb/yjij family mfs transporterEC600_00010Not AvailablePositive684 - 182941961.1
Ncrna_class:rnase_p_rnaNot AvailableNot AvailablePositive1569 - 1888Not Available
gtp-binding proteinEC600_00015Not AvailableNegative2014 - 297635915.7
hypothetical proteinEC600_00020Not AvailableNegative2976 - 335314237.0
polysaccharide deacetylaseEC600_00025Not AvailableNegative3400 - 428133701.4
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive4563 - 4660Not Available

Displaying genes 1 – 10 of 1640 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Peptic ulcer diseaseCausesPMC5203880
Gastric adenocarcinomaCausesPMC5203880
Mucosa-associated lymphoid tissue (malt) lymphomaCausesPMC5203880
Peptic ulcer diseaseCausesPMC7037374
GastritisCausesPMC7037374
Gastric cancerCausesPMC7037374
Functional dyspepsiaCausesPMC7037374
GastritisCausesPMC7459201
Gastric cancerCausesPMC7459201
Intestinal diseasesCausesPMC7459201

Displaying health effects 31 – 40 of 94 in total