Helicobacter pylori str. ZH134

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH134 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives at an optimal temperature of 37.0°C, which aligns with its adaptation to a host-associated habitat, typically found in the gastric mucosa of mammals. The microaerophilic nature of H. pylori indicates that it requires reduced oxygen levels for optimal growth, which is consistent with its ecological niche within the stomach, where oxygen availability is limited. The unique spiral morphology of H. pylori contributes to its motility within the viscous gastric environment, allowing it to navigate through mucus layers and adhere to the epithelial cells. This adaptation is crucial for its survival and potential interactions with the host's immune system. Understanding the specific growth conditions and morphological traits of H. pylori strain ZH134 can provide insights into its role in the gastric ecosystem, as well as its interactions with host physiology. Further research may elucidate the microbial dynamics and host responses associated with this strain, potentially revealing its significance in health and disease contexts.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH134

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH134
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH134 191, whole genome shotgun

Gene Summary

Adenine Count

503318 bp

Thymine Count

503543 bp

Guanine Count

323683 bp

Cytosine Count

317830 bp

Genome Length

1661632 bp

Protein-coding Genes

1598 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dead/deah box helicaseEC600_00330Not AvailableNegative72366 - 7384455812.3
flagellar basal body p-ring protein flgiEC600_00335Not AvailablePositive74032 - 7506036607.7
hypothetical proteinEC600_00340Not AvailablePositive75057 - 7537412127.6
ghkl domain-containing proteinEC600_00345Not AvailablePositive75371 - 7651643694.5
dna starvation/stationary phase protection proteinEC600_00350Not AvailablePositive76724 - 7715816809.1
duf2018 family proteinEC600_00355Not AvailablePositive77179 - 7746311135.3
hypothetical proteinEC600_00360Not AvailablePositive77456 - 7785115498.8
polyprenyl synthetase family proteinEC600_00365Not AvailablePositive77861 - 7878435085.6
glutamyl-trna reductaseEC600_00370Not AvailablePositive78784 - 8013351806.8
proline--trna ligaseEC600_00375Not AvailablePositive80137 - 8187065007.4

Displaying genes 71 – 80 of 1640 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total