Helicobacter pylori str. ZH129

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH129 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain thrives optimally at a temperature of 37.0°C, typically reflecting the physiological conditions of its host environment. As a member of the Helicobacter genus, H. pylori is primarily associated with the gastric mucosa of various hosts, indicating a specialized niche that aligns with its habitat preferences. The microaerophilic nature of H. pylori suggests that it requires reduced levels of oxygen for growth, which is consistent with its colonization of the gastric environment where oxygen concentrations are lower than atmospheric levels. This adaptation allows H. pylori to thrive in the highly acidic conditions of the stomach, where it plays a complex role within the host’s microbiome. The specific habitat and growth requirements of H. pylori strain ZH129 may provide insights into its metabolic pathways and interactions within the gastrointestinal microbiota. Understanding these traits is crucial for elucidating the ecological dynamics of H. pylori in its host and could inform future research on its role in health and disease. The capacity of H. pylori to adapt to microaerophilic conditions in a host-associated environment highlights the intricate relationships that exist within microbial communities and their hosts, emphasizing the need for further investigation into the ecological implications of such specialized adaptations.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH129

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH129
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH129 51, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dihydroneopterin aldolaseEC595_01325Not AvailablePositive257730 - 25806513053.9
16s rrna (guanine(966)-n(2))-methyltransferase rsmdEC595_01330Not AvailablePositive258044 - 25864622404.4
flagellar basal body-associated protein flilEC595_01335Not AvailablePositive258655 - 25920620365.8
holo-acp synthaseEC595_01340Not AvailablePositive259213 - 25957213106.2
ligand-gated channelEC595_01345Not AvailablePositive259781 - 26215989465.4
m48 family peptidaseEC595_01350Not AvailableNegative262170 - 26279024123.6
glycosyltransferase family 25 proteinEC595_01355Not AvailablePositive262872 - 26372632860.5
bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase iiEC595_01360Not AvailablePositive263896 - 26493038881.2
duf3943 domain-containing proteinEC595_01365Not AvailablePositive265019 - 26585832148.8
gtp cyclohydrolase iiEC595_01370Not AvailablePositive265947 - 26652521725.2

Displaying genes 251 – 260 of 1518 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total