Helicobacter pylori str. ZH02

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH02 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This strain exhibits optimal growth at a temperature of 37.0 °C, which aligns with its habitat as a host-associated organism. The microaerophilic nature of H. pylori indicates that it thrives in environments with reduced oxygen levels, which is characteristic of the gastric mucosa where it is often found. This bacterium plays a significant role in the human gastrointestinal tract, particularly in the stomach, where it can influence the host's microbiome and potentially contribute to various gastric conditions. The single-cell arrangement of H. pylori suggests a lifestyle that may be adapted for niche colonization within the gastric environment, allowing for efficient interaction with host tissues and evasion of immune responses. The specific adaptation to a microaerophilic habitat underscores the evolutionary strategies employed by H. pylori to thrive in the acidic gastric milieu, where oxygen levels are limited. Understanding these traits can provide insights into the ecological dynamics of H. pylori within the human digestive system and its potential impact on gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH02

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH02
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH02 32, whole genome shotgun sequence.

Gene Summary

Adenine Count

472978 bp

Thymine Count

472060 bp

Guanine Count

300888 bp

Cytosine Count

306565 bp

Genome Length

1554839 bp

Protein-coding Genes

1418 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tonb-dependent receptorECB89_03485Not AvailablePositive691017 - 69339288456.0
crossover junction endodeoxyribonuclease ruvcECB89_03490Not AvailableNegative693393 - 69386617439.5
nyn domain-containing proteinECB89_03495Not AvailablePositive693998 - 69472328186.7
hypothetical proteinECB89_03500Not AvailableNegative694789 - 6950259009.65
duf3519 domain-containing proteinECB89_03510Not AvailableNegative695779 - 69645925626.3
holliday junction branch migration protein ruvaECB89_03515Not AvailableNegative696546 - 69709720220.1
duf342 domain-containing proteinECB89_03520Not AvailableNegative697123 - 69896770962.1
murein biosynthesis integral membrane protein murjECB89_03525Not AvailablePositive699060 - 70052054527.8
cysteine--trna ligaseECB89_03530Not AvailablePositive700521 - 70191853126.7
autotransporter domain-containing proteinECB89_03535Not AvailablePositive702141 - 706079142363.0

Displaying genes 661 – 670 of 1460 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total