Helicobacter pylori str. ZH02

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH02 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and single-cell arrangement. This strain exhibits optimal growth at a temperature of 37.0 °C, which aligns with its habitat as a host-associated organism. The microaerophilic nature of H. pylori indicates that it thrives in environments with reduced oxygen levels, which is characteristic of the gastric mucosa where it is often found. This bacterium plays a significant role in the human gastrointestinal tract, particularly in the stomach, where it can influence the host's microbiome and potentially contribute to various gastric conditions. The single-cell arrangement of H. pylori suggests a lifestyle that may be adapted for niche colonization within the gastric environment, allowing for efficient interaction with host tissues and evasion of immune responses. The specific adaptation to a microaerophilic habitat underscores the evolutionary strategies employed by H. pylori to thrive in the acidic gastric milieu, where oxygen levels are limited. Understanding these traits can provide insights into the ecological dynamics of H. pylori within the human digestive system and its potential impact on gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH02

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH02
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH02 32, whole genome shotgun sequence.

Gene Summary

Adenine Count

472978 bp

Thymine Count

472060 bp

Guanine Count

300888 bp

Cytosine Count

306565 bp

Genome Length

1554839 bp

Protein-coding Genes

1418 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribonuclease yECB89_02905Not AvailableNegative578248 - 57983760259.7
5-formyltetrahydrofolate cyclo-ligaseECB89_02910Not AvailableNegative579737 - 58041126469.8
hypothetical proteinECB89_02915Not AvailablePositive580509 - 58106621201.7
signal recognition particle-docking protein ftsyECB89_02920Not AvailablePositive581072 - 58195332615.7
gtp 3',8-cyclase moaaECB89_02940Not AvailableNegative584639 - 58560436581.6
molybdenum cofactor guanylyltransferase mobaECB89_02945Not AvailablePositive585690 - 58629522850.8
flagellar biosynthesis protein flhbECB89_02950Not AvailablePositive586288 - 58736440991.0
hypothetical proteinECB89_02955Not AvailableNegative587459 - 58819628843.3
n-acetylmuramoyl-l-alanine amidaseECB89_02960Not AvailableNegative588215 - 58952249175.3
nitronate monooxygenaseECB89_02965Not AvailableNegative589529 - 59062039566.1

Displaying genes 551 – 560 of 1460 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total