Helicobacter pylori str. ZH01

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. ZH01 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This strain is optimally adapted to growth at 37.0°C, a temperature that aligns with its natural habitat in the gastric environment of its host. As a member of the Helicobacter genus, H. pylori str. ZH01 is typically found associated with the mucosal lining of the stomach, where it plays a complex role in the gastrointestinal microbiome. The microaerophilic nature of H. pylori str. ZH01 indicates that it thrives in environments with reduced oxygen levels, which is consistent with the low-oxygen conditions found in the gastric niche. This adaptation is essential for its survival and metabolic activities within the host. The strain's unique morphology and growth conditions suggest an evolutionary specialization that may provide insights into its interactions with host gastric physiology. Understanding the specific traits of Helicobacter pylori str. ZH01 contributes to the broader knowledge of microbial diversity in host-associated environments and underscores the intricate relationship between bacteria and their hosts. This strain exemplifies how microbial adaptations to specific habitats can influence both ecological dynamics and the overall health of the host organism.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainZH01

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. ZH01
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain ZH01 47, whole genome shotgun sequence.

Gene Summary

Adenine Count

498425 bp

Thymine Count

495377 bp

Guanine Count

318271 bp

Cytosine Count

313742 bp

Genome Length

1629349 bp

Protein-coding Genes

1485 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenine methyltransferaseECB88_05225Not AvailablePositive1012513 - 101351438957.1
dam family site-specific dna-(adenine-n6)-methyltransferaseECB88_05230Not AvailablePositive1013511 - 101441035348.3
outer membrane proteinECB88_05240Not AvailableNegative1016093 - 101725943021.1
copper resistance protein copdECB88_05245Not AvailablePositive1017439 - 10177039801.38
fucosyltransferaseECB88_05250Not AvailableNegative1017704 - 10178576160.43
phosphoserine phosphatase serbECB88_05255Not AvailableNegative1017902 - 101852523054.2
non-heme ferritinECB88_05260Not AvailableNegative1018540 - 101904319302.8
aminofutalosine synthase mqneECB88_05265Not AvailablePositive1019339 - 102042141324.9
outer membrane protein assembly factor bamaECB88_05270Not AvailablePositive1020504 - 1023254102835.0
dehypoxanthine futalosine cyclaseECB88_05275Not AvailablePositive1023166 - 102431743495.8

Displaying genes 991 – 1000 of 1527 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total