Helicobacter pylori str. 45

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 45 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives optimally at 37.0 °C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. H. pylori strain 45 exhibits microaerophilic oxygen requirements, suggesting that it prefers environments with lower oxygen levels than those found in the atmosphere, which is consistent with its colonization of the gastric mucosa in the stomach. The unique morphological and physiological traits of H. pylori strain 45 facilitate its survival and persistence in the harsh acidic environment of the stomach. Its curved shape allows for motility through the viscous gastric mucus, while its microaerophilic nature enables it to thrive in oxygen-restricted niches. By residing in the gastric environment, this strain likely plays a role in the complex microbial ecosystem of the human gut, where it may influence local pH levels and interact with other resident microorganisms. Understanding the specific adaptations of H. pylori strain 45 can provide insights into its ecological role and its potential impacts on gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain45

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 45
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 45 Contig55, whole genome shotgun

Gene Summary

Adenine Count

504266 bp

Thymine Count

500853 bp

Guanine Count

322607 bp

Cytosine Count

314892 bp

Genome Length

1642618 bp

Protein-coding Genes

1523 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rna polymerase subunit sigmaAM497_00405Not AvailableNegative81726 - 8376878728.8
s-adenosylhomocysteine nucleosidaseAM497_00410Not AvailableNegative84047 - 8474225106.4
malonyl coa-acp transacylaseAM497_00415Not AvailableNegative84753 - 8568234356.8
Trna-serNot AvailableNot AvailablePositive85812 - 85903Not Available
restriction endonucleaseAM497_00425Not AvailablePositive86109 - 8694232506.8
dna methylase n-4AM497_00430Not AvailablePositive86936 - 8779032633.2
alpha-1,2-fucosyltransferaseAM497_00435Not AvailableNegative87787 - 8822717152.7
tautomeraseAM497_00440Not AvailableNegative88463 - 886697498.04
recombinase recrAM497_00445Not AvailablePositive88830 - 8941122049.6
pseudouridine synthaseAM497_00450Not AvailablePositive89408 - 9055344040.2

Displaying genes 81 – 90 of 1564 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total