Helicobacter pylori str. 45

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 45 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives optimally at 37.0 °C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. H. pylori strain 45 exhibits microaerophilic oxygen requirements, suggesting that it prefers environments with lower oxygen levels than those found in the atmosphere, which is consistent with its colonization of the gastric mucosa in the stomach. The unique morphological and physiological traits of H. pylori strain 45 facilitate its survival and persistence in the harsh acidic environment of the stomach. Its curved shape allows for motility through the viscous gastric mucus, while its microaerophilic nature enables it to thrive in oxygen-restricted niches. By residing in the gastric environment, this strain likely plays a role in the complex microbial ecosystem of the human gut, where it may influence local pH levels and interact with other resident microorganisms. Understanding the specific adaptations of H. pylori strain 45 can provide insights into its ecological role and its potential impacts on gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain45

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 45
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 45 Contig55, whole genome shotgun

Gene Summary

Adenine Count

504266 bp

Thymine Count

500853 bp

Guanine Count

322607 bp

Cytosine Count

314892 bp

Genome Length

1642618 bp

Protein-coding Genes

1523 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinAM497_02490Not AvailableNegative467578 - 46886749394.0
tat pathway signal sequence domain proteinAM497_02495Not AvailableNegative469133 - 46939910156.3
aconitate hydratase 2AM497_02500Not AvailableNegative469480 - 47203892763.9
menaquinone biosynthesis proteinAM497_02505Not AvailablePositive472169 - 47285226671.8
uridylate kinaseAM497_02510Not AvailablePositive472961 - 47368326174.0
dna-directed rna polymerase subunit omegaAM497_02515Not AvailablePositive473725 - 4739498505.4
penta-phosphate guanosine-3'-pyrophosphohydrolaseAM497_02520Not AvailablePositive473936 - 47626389088.7
tyrosyl-trna synthetaseAM497_02525Not AvailablePositive476287 - 47749545571.1
2-nitropropane dioxygenaseAM497_02530Not AvailablePositive477512 - 47860339594.2
n-acetylmuramoyl-l-alanine amidaseAM497_02535Not AvailablePositive478610 - 47994150161.4

Displaying genes 491 – 500 of 1564 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total