Helicobacter pylori str. 45

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 45 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives optimally at 37.0 °C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. H. pylori strain 45 exhibits microaerophilic oxygen requirements, suggesting that it prefers environments with lower oxygen levels than those found in the atmosphere, which is consistent with its colonization of the gastric mucosa in the stomach. The unique morphological and physiological traits of H. pylori strain 45 facilitate its survival and persistence in the harsh acidic environment of the stomach. Its curved shape allows for motility through the viscous gastric mucus, while its microaerophilic nature enables it to thrive in oxygen-restricted niches. By residing in the gastric environment, this strain likely plays a role in the complex microbial ecosystem of the human gut, where it may influence local pH levels and interact with other resident microorganisms. Understanding the specific adaptations of H. pylori strain 45 can provide insights into its ecological role and its potential impacts on gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain45

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 45
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 45 Contig55, whole genome shotgun

Gene Summary

Adenine Count

504266 bp

Thymine Count

500853 bp

Guanine Count

322607 bp

Cytosine Count

314892 bp

Genome Length

1642618 bp

Protein-coding Genes

1523 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
preprotein translocase subunit seceAM497_06000Not AvailableNegative1192408 - 11925876669.46
Trna-trpNot AvailableNot AvailablePositive1192730 - 1192805Not Available
50s ribosomal protein l33AM497_06010Not AvailableNegative1192845 - 11930036066.43
elongation factor tuAM497_06015Not AvailableNegative1193037 - 119423643638.4
Trna-thrNot AvailableNot AvailablePositive1194363 - 1194437Not Available
Trna-glyNot AvailableNot AvailablePositive1194468 - 1194544Not Available
Trna-tyrNot AvailableNot AvailablePositive1194561 - 1194645Not Available
Trna-thrNot AvailableNot AvailablePositive1194673 - 1194748Not Available
multidrug transporterAM497_06040Not AvailablePositive1194935 - 119667166283.8
hydrolaseAM497_06045Not AvailableNegative1196680 - 119734825513.5

Displaying genes 1171 – 1180 of 1564 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total